# R3EDI - Rigorous, Rapid, & Relevant Evidence aDaptation & Implementation to EHE

> **NIH NIH P30** · YALE UNIVERSITY · 2021 · $418,561

## Abstract

Project Summary/Abstract
Although there are effective prevention and treatment tools available to end the HIV epidemic, their impact on
reducing HIV incidence, morbidity, and mortality in the United States has been limited by challenges in
identifying and deploying those that are feasible, acceptable, and sustainable. Implementation science (IS) can
be used to overcome these challenges; thus, increasing IS capacity is critical for HIV prevention and treatment
efforts. As interest increases for IS Ending the HIV Epidemic (EHE) projects, need for IS consultation, technical
support, and capacity building is expanding commensurately. Leveraging the expertise of Yale's Center for
Methods in Implementation and Prevention Science and Center for Interdisciplinary Research on AIDS, we will
continue the work of our R3EDI (Rigorous, Rapid, & Relevant Evidence aDaptation & Implementation) IS
consultation hub to EHE, providing technical assistance, coaching, training, and consultative services to EHE
project teams, HIV researchers and federal agencies, in collaboration with the IS Coordination, Consultation
and Collaboration Initiative (ISC3I), creating opportunities to translate local knowledge into generalizable
knowledge whenever possible. R3EDI offers comprehensive expertise in IS methods, frameworks, strategies,
measures and outcomes in HIV/AIDS research, design and management of experimental and observational IS
studies, data collection, sampling; quantitative, qualitative, and mixed-methods analytic approaches; public
health ethics, partnership formation, and community-based participatory research. With ISC3I, R3EDI will
collect data on measures and outcomes from projects served, providing data requested by NIH/HHS for these
projects. We will collaborate with ISC3I and the other IS technical assistance hubs around the country in the
design and conduct of a multisite pilot implementation research study to further advance EHE efforts, engaging
implementation partners and developing the shared protocol in Year 1, executing the protocol and harmonizing
findings in Year 2. We will collaborate with the inter-Centers for AIDS Research HIV-related Training
Fellowship in IS, providing technical expertise and mentoring as needed. As part of efforts to broaden the
reach of our collective HIV IS technical assistance, ISC3I and the Hubs will form a working group to support the
IS needs of federal partners (e.g., CDC, HRSA) and non-supplement projects (e.g., EHE R01s) focused on
HIV IS. R3EDI's activities will maximize IS rigor, rapidity, and relevance in EHE projects and within the ISC3I-
led cross-hub collaboration, increasing partnerships, and ensuring consultees receive effective, timely services
having an impact beyond this supplement, leading to future collaborations between us and EHE researchers.

## Key facts

- **NIH application ID:** 10420035
- **Project number:** 3P30MH062294-19S2
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** Trace S Kershaw
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $418,561
- **Award type:** 3
- **Project period:** 2001-09-30 → 2023-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10420035

## Citation

> US National Institutes of Health, RePORTER application 10420035, R3EDI - Rigorous, Rapid, & Relevant Evidence aDaptation & Implementation to EHE (3P30MH062294-19S2). Retrieved via AI Analytics 2026-06-10 from https://api.ai-analytics.org/grant/nih/10420035. Licensed CC0.

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