# Live Cell Fluorescent Imaging System

> **NIH NIH S10** · WAKE FOREST UNIVERSITY · 2022 · $249,903

## Abstract

PROJECT SUMMARY/ABSTRACT
A developing area of focus for Wake Forest University is the investigation of cellular and molecular
aspects of microbial organisms. Novel research goals being pursued by these study teams will
uncover detailed biochemical mechanisms within microbes that have direct relevance to human health
and disease states. Microscopy represents a critical tool for all the studies outlined here with
investigators collectively proposing emphasis on morphologic data measures that require acquisition
of exceptional quality fluorescent and brightfield images. While the Wake Forest Microscopic Imaging
Core Facility has been an historic area of strength for the Department of Biology, current needs are
exceeding the available equipment capabilities in terms of both specific functionality and available
imaging time. The Leica Thunder Live Cell Imager system requested here represents an ideal
platform for meeting the directed research goals and plans outlined in this proposal. It will expand our
existing capabilities by providing a high-speed fluorescence acquisition system with optimized living
tissue imaging conditions, and will provide a new approach for automated large sample territory
visualization and detailed image acquisition. In addition to providing equipment that will be crucial to
carry out the directed activities outlined here, this system will serve as a key addition to broaden our
extant technical framework that stimulates and supports microscopic investigations of biology and
human health in our region.

## Key facts

- **NIH application ID:** 10424798
- **Project number:** 1S10OD032281-01
- **Recipient organization:** WAKE FOREST UNIVERSITY
- **Principal Investigator:** Glen Marrs
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $249,903
- **Award type:** 1
- **Project period:** 2022-06-01 → 2023-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10424798

## Citation

> US National Institutes of Health, RePORTER application 10424798, Live Cell Fluorescent Imaging System (1S10OD032281-01). Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/grant/nih/10424798. Licensed CC0.

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