# Clinical and Translational Science Core

> **NIH NIH P30** · UNIVERSITY OF WASHINGTON · 2022 · $223,703

## Abstract

PROJECT SUMMARY (CLINICAL AND TRANSLATIONAL SCIENCE CORE)
The WHO’s “End TB Strategy” will require novel TB vaccines, drugs, and diagnostics, along with advances in
clinical research methods and modeling, a new cadre of clinical researchers, strengthened domestic and
international collaborations, and access to biospecimens. The University of Washington (UW) excels in
conducting research in clinical epidemiology, clinical trials, implementation science, and disease modeling, while
also developing strong global health programs and partnerships in TB-endemic countries. The Clinical and
Translational Science Core (“CTSC”) will educate and train new and early-stage investigators, including people
working in TB-endemic countries, and individuals from underrepresented minority groups, in critical areas of
clinical TB research. The CTSC will coordinate with the other SEA-TRAC Cores to leverage the multi-disciplinary
expertise available and engage non-TB investigators who may bring novel perspectives and advanced methods
to TB research. The CTSC will leverage existing biorepositories to catalyze TB research and generate
preliminary data using the vast UW research network that includes field sites in Latin America, sub-Saharan
Africa, and Asia. The CTSC will be to provide expertise for a broad array of clinical research topics, provide
shared research support for resources, services and training, and to strengthen TB clinical research through
domestic and international collaborations through three specific aims: (1) to strengthen clinical and translational
TB research through training and consultation in clinical science methodology and support of local collaborations;
(2) to strengthen TB clinical research by developing and expanding partnerships with national and international
collaborators conducting clinical and translational research in TB; and (3) Aim 3. To foster and catalyze
collaborations with investigators with established cohorts, robust clinical databases, and biospecimens for
advancing basic, translation, and clinical TB research. The CTSC will also maintain an intensive one-week
advanced TB research summer course. Overall, the CTSC will foster collaborations between SEA-TRAC
investigators and authorizing investigators, which will lead to more productive and efficient research, an increase
in generated pilot study data, and more collaborative TB grant submissions over a 5-year period.

## Key facts

- **NIH application ID:** 10425950
- **Project number:** 1P30AI168034-01
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** David J. Horne
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $223,703
- **Award type:** 1
- **Project period:** 2022-03-21 → 2027-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10425950

## Citation

> US National Institutes of Health, RePORTER application 10425950, Clinical and Translational Science Core (1P30AI168034-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10425950. Licensed CC0.

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