# Infectious Disease/Basic Microbial Pathogenic Mechanisms

> **NIH NIH T32** · WASHINGTON UNIVERSITY · 2022 · $585,190

## Abstract

PROJECT ABSTRACT
This is an application to renew the Infectious Diseases/Basic Microbial Pathogenesis Training Grant from
Washington University. With the advent of generally available antibiotic therapy about 50 years ago, many
physicians and scientists predicted the end of infectious diseases as a major area of health concern.
Subsequent events have proven this prediction wrong, and the past decades have seen the emergence of
many newly identified infectious diseases, including Lyme Disease, erlichiosis, SARS, COVID-19, West Nile
encephalitis, chikungunya, MERS, ebola and HIV. The reemergence of old infectious diseases, such as
malaria and tuberculosis, in more virulent and more antibiotic resistant forms also has increased public
attention on the health problems posed by infectious diseases. It is rare that a week goes by without some
troubling headline concerning new infectious disease outbreaks. Thus, far from gradual disappearance as a
health concern, infectious diseases have emerged as being of increasing importance to the health concerns
of the nation. The emerging antibiotic resistance of current pathogens and the rise of new disease agents
have made clear the necessity of increased fundamental scientific investigation into all aspects of infectious
diseases. The purpose of the Washington University Training Program in Infectious Diseases/Basic Microbial
Pathogenesis is to help fulfill this need by recruiting promising young investigators to this field and training
them in outstanding research programs with preeminent investigators who collaborate across multiple
disciplines (or who function in interdisciplinary teams) to perform infectious disease research. Our Training
Program, which has had NIH support for the past 40 years, integrates faculty from four departments:
Medicine, Pediatrics, Molecular Microbiology and Pathology & Immunology. The program provides training to
M.D., Ph.D., and M.D./Ph.D. postdoctoral fellows, and to Ph.D. and M.D./Ph.D. students, in disciplines
related to pathogenesis and host defense in Infectious Diseases. The laboratories of the program preceptors
use tools of molecular biology, biochemistry, genetics, genomics, immunology, cell biology and translational
medicine. Thus, the program trains young investigators to be able to answer the important questions of
microbial pathogenesis, from studies of basic biology through application to the bedside.

## Key facts

- **NIH application ID:** 10426341
- **Project number:** 5T32AI007172-42
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** Daniel E. Goldberg
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $585,190
- **Award type:** 5
- **Project period:** 1980-09-15 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10426341

## Citation

> US National Institutes of Health, RePORTER application 10426341, Infectious Disease/Basic Microbial Pathogenic Mechanisms (5T32AI007172-42). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10426341. Licensed CC0.

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