# Connectome style neuroimaging in non human primates via novel integrated RF platforms

> **NIH NIH R56** · UNIVERSITY OF MINNESOTA · 2021 · $502,102

## Abstract

PROJECT SUMMARY
Ultra high field neuroimaging in humans enables unprecedented resolutions that enable, for the 
first time, the non invasive investigation of directional information processing in vivo. These 
advances result from the ability of high resolutions to uncover layer specific (feedforward, 
feedback) activation patterns. These tools however are not validated in translational models that 
mimic human brain function. The reason for that is primarily due  to our current inability to 
obtain functional magnetic resonance imaging (fMRI) signals at resolutions high enough to resolve 
layer specific responses in the non human primate. This project aims at developing novel and 
innovative radiofrequency hardware and using it at the ultra high field strength of 10.5 Tesla to 
directly test how well whole brain directional connectivity estimates from fMRI correspond with 
ground truth tract tracing experiments. This development and validation can directly aid us in 
translating findings from the animal model into future studies of the mesoscopic circuit effects of 
human mental illness.

## Key facts

- **NIH application ID:** 10426505
- **Project number:** 1R56EB031765-01
- **Recipient organization:** UNIVERSITY OF MINNESOTA
- **Principal Investigator:** Jan Zimmermann
- **Activity code:** R56 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $502,102
- **Award type:** 1
- **Project period:** 2021-09-30 → 2022-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10426505

## Citation

> US National Institutes of Health, RePORTER application 10426505, Connectome style neuroimaging in non human primates via novel integrated RF platforms (1R56EB031765-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10426505. Licensed CC0.

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