# Mentorship in Precision Pain Medicine via EPPIC-NET

> **NIH NIH K24** · BRIGHAM AND WOMEN'S HOSPITAL · 2021 · $318,913

## Abstract

Abstract
The Early Phase Pain Investigation Clinical Network (EPPIC-Net) is designed to rapidly and efficiently
translate advances in the neurobiology of pain into treatments for people with chronic and acute pain,
conditions associated with a significant burden to both patients and society. Dr. Edwards is one of the
Principal Investigators of EPPIC-Net’s Clinical Coordinating Center (CCC); the primary goal of the CCC for
EPPIC-Net is to promote and facilitate, from initial conception through final analysis, clinical trials in adult
and pediatric populations with acute or chronic pain by providing efficient methodological, organizational
and logistical support. One of the CCC’s Specific Aims is to expand the pool of experienced clinical
Investigators and research staff to be participants and leaders of multicenter clinical research trials by
providing education, training, resources and professional mentorship. This K24 would allow Dr. Edwards to
increase the amount of time he spends mentoring junior pain scientists. Much of this mentoring will involve
work on precision pain medicine, including biomarker validation studies, and deep phenotyping of patient
populations to understand the biologic basis of a specific pain condition and its response to treatment.
Collectively, there is an urgent need for more research to establish best practices in clinical pain
management, and a limited workforce pipeline of clinical pain researchers to meet NIH’s long-term goals of
providing effective non-opioid options for the treatment of pain conditions. Increasing the supply and
availability of mentors in the field with the goal of mentoring a new generation of diverse and highly skilled
clinical pain researchers is a critically-important goal addressed by this K24. This project would efficiently
leverage current HEAL funding (for the EPPIC-Net CCC) to encourage an interest in the field of clinical pain
management, generate innovative research projects, and increase the number of clinical researchers,
especially research from diverse background, trained in high-quality clinical pain research.

## Key facts

- **NIH application ID:** 10426787
- **Project number:** 1K24NS126570-01
- **Recipient organization:** BRIGHAM AND WOMEN'S HOSPITAL
- **Principal Investigator:** ROBERT R EDWARDS
- **Activity code:** K24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $318,913
- **Award type:** 1
- **Project period:** 2021-09-30 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10426787

## Citation

> US National Institutes of Health, RePORTER application 10426787, Mentorship in Precision Pain Medicine via EPPIC-NET (1K24NS126570-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10426787. Licensed CC0.

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