Project Summary This shared instrumentation proposal request funds to support the upgrade of the 7T magnetic resonance imaging (MRI) system at the UCSD Center for Functional MRI (CFMRI). The current system utilizes a Bruker AVANCE II console that was installed in 2007. Bruker is no longer guaranteeing support for the AVANCE II platform and the inventory of available spare parts for the console is rapidly dwindling. As a result, the likelihood of prolonged periods of downtime on the system is continually increasing and threatens the ability to carry out a wide range of ongoing NIH-funded projects at UCSD, including studies of cancer, osteoarthritis, heart failure, and memory. An upgrade to a console (AVANCE NEO) that is fully supported by Bruker is critical to minimize downtime and ensure the success of these important projects. As the AVANCE NEO console is designed to work seamlessly with the existing Bruker 7T USR magnet at the CFMRI, the proposed upgrade will ensure a smooth transition to a solution that can readily support the progress of ongoing NIH-funded studies.