# Multimodality PET/CT Scanner for Small Animal Imaging

> **NIH NIH S10** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2022 · $878,156

## Abstract

PROJECT SUMMARY/ABSTRACT
The goal of this proposal is to secure funding for an instrument dedicated to in vivo imaging of small animal
models of human diseases via integrated positron emission tomography (PET)/X-ray computed tomography
(CT). The instrument we propose is the GNEXT PET/CT system manufactured by Sofie Biosciences Inc. The
PET component offers a high-resolution, high-sensitivity, and versatile platform for small-animal molecular
imaging. The CT component is a fast, high-resolution system that enables sequential scanning for anatomy
alongside molecular imaging by PET. This system will replace obsolete, stand-alone PET and CT scanners
which are no longer supported by the manufacturer and for which certain key components are no longer
available. The lack of support for these existing scanners is a major vulnerability for a wide range of preclinical
imaging research at our institution. The PET/CT scanner will be installed at the UC Davis Center for Molecular
and Genomic Imaging (CMGI), which is a campus-designated and supported core facility providing infrastructure
and expertise to conduct in vivo imaging studies in small-animal models. CMGI oversees a cyclotron and
radiochemistry facilities dedicated to preclinical imaging research and provides a wide range of tracers and
radioligands that will be available to use with the proposed scanner. Institutional support provided to the CMGI
ensures its successful operation and maintenance for its lifetime. The instrument will support at least 11 major
and minor users who are conducting NIH-funded research in diverse areas such as neurology, oncology,
rheumatology, orthopaedics, nanotechnology and biomedical engineering.

## Key facts

- **NIH application ID:** 10429458
- **Project number:** 1S10OD030440-01A1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** Abhijit J Chaudhari
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $878,156
- **Award type:** 1
- **Project period:** 2022-04-15 → 2023-07-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10429458

## Citation

> US National Institutes of Health, RePORTER application 10429458, Multimodality PET/CT Scanner for Small Animal Imaging (1S10OD030440-01A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10429458. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*