# Vaccine and Treatment Evaluation Units (VTEU)-DMID 21-0004

> **NIH NIH UM1** · BAYLOR COLLEGE OF MEDICINE · 2021 · $308,091

## Abstract

BAYLOR COLLEGE OF MEDICINE- ABSTRACT
The purpose of this study is to evaluate the immunogenicity and safety of various licensed or EUA
SARS-CoV-2 vaccines administered to pregnant or lactating women and describe the
transplacental antibody transfer and kinetics of antibodies in infants. We will also evaluate the
durability of the antibodies in mothers and infants and assess breast milk antibodies in lactating
women. We will evaluate breast milk antibodies to assess potential for protection against COVID-
19 in breastfed infants, similar to influenza vaccine protection from influenza illness in infants of
mothers vaccinated during pregnancy or postpartum. We anticipate including up to 5 vaccines as
part of this non-interventional study. It is expected that the results of this study will inform policy
recommendations and personal decision-making on the use of approved SARS-CoV-2 vaccines
in pregnant and lactating individuals.

## Key facts

- **NIH application ID:** 10429608
- **Project number:** 3UM1AI148575-02S8
- **Recipient organization:** BAYLOR COLLEGE OF MEDICINE
- **Principal Investigator:** HANA M EL SAHLY
- **Activity code:** UM1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $308,091
- **Award type:** 3
- **Project period:** 2021-07-15 → 2024-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10429608

## Citation

> US National Institutes of Health, RePORTER application 10429608, Vaccine and Treatment Evaluation Units (VTEU)-DMID 21-0004 (3UM1AI148575-02S8). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10429608. Licensed CC0.

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