# National Alzheimer's Coordinating Center

> **NIH NIH U24** · UNIVERSITY OF WASHINGTON · 2021 · $786,494

## Abstract

PROJECT SUMMARY
The Covid-19 pandemic has had a substantial impact on vulnerable aging populations across the world.
Clinical care of patients with Alzheimer’s associated dementia are especially vulnerable to the effects of Covid-
19 and Covid-19 has been associated with poor outcomes in patients. In this National Alzheimer’s
Coordinating Center (NACC) Administrative Supplement proposal, we are providing the infrastructure for
investigating the genetic factors associated with poor outcomes in patients with AD and a history of Covid-19.
We are leveraging and deploying new data collection instruments for Covid-19 phenotypes to the Alzheimer’s
Disease Research Centers Consortium (ADRCs). This work will provide a high impact, innovative, and
economical demonstration of the use of routine clinical care data to quantitatively and accurately phenotype
patients. Care data in the form of Centers for Medicare and Medicaid Services (CMS) administrative claims
and electronic health record (EHR) will be the basis for this demonstration. NACC will collaborate with
NIAGADS and three pilot sites, Washington University St. Louis, Columbia University and Indiana University
ADRCs. This work will be done in three aims. First, we will support additional clinical research at the pilot
clinical sites and will deploy new prospective data collection instruments to support post acute sequelae of
Covid-19. Second, we will assess feasibility of and begin to collect EHR and CMS data in partnership with the
ADRC pilot sites and the NIA. Finally, we will collaborate with NIAGADS to enable collaborative analysis of
integrated phenotype and genetic data of enrolled participant data. Together this proposal, if funded, will place
important infrastructure for the study of AD associated phenotypes and Covid-19.

## Key facts

- **NIH application ID:** 10430699
- **Project number:** 3U24AG072122-01S1
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** Walter Anthony Kukull
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $786,494
- **Award type:** 3
- **Project period:** 2021-06-15 → 2026-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10430699

## Citation

> US National Institutes of Health, RePORTER application 10430699, National Alzheimer's Coordinating Center (3U24AG072122-01S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10430699. Licensed CC0.

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