The Developmental Core: The goals of the Developmental Core are the same as the overall Tri-Institutional TB Research Advancement Center (Tri-I TRAC): 1) To increase the number of NIH funded investigators conducting basic, clinical and translational research in TB and 2) To foster multidisciplinary TB research with a focus on NIAID’s five priorities for TB science. To do so, the Developmental Core will solicit, review and fund one year Developmental Project Awards of $50,000 that will help NIs and N2TB investigators generate preliminary data for future R01s or other grant applications by coordinating access to the Basic Science and Clinical Cores, along with structured mentorship and professional networking. Together, these activities will create a Training to Independence Pathway for NIs. It will provide 6 awards per year, two of which will be supported annually by Weill Cornell institutional funds to promote diversity. In addition to this primary role, the Developmental Science Core will also bolster the pipeline of NIs in TB research by: introducing undergraduates and graduate students to the field; helping to increase the competitive standing of graduate students for postdoctoral fellowships in the field; and encouraging physician post-doctoral fellows to enter TB research. The Developmental Science Core will thus enable a sustainable pipeline of new investigators and collaborative translational research focused on the five NIAID priorities in TB science and ultimate goal of ending morbidity and mortality from TB worldwide.