# Developmental Core

> **NIH NIH P30** · JOHNS HOPKINS UNIVERSITY · 2022 · $285,097

## Abstract

ABSTRACT – JHU TRAC DEVELOPMENTAL CORE (DC)
The mission of the Developmental Core (DC) is to support and mentor the next generation of TB researchers
and to recruit new TB investigators to increase the diversity and breadth of TB scientists at Johns Hopkins
University (JHU). Early Stage Investigators (ESI) need to integrate a variety of disciplines into their work, and
innovative leaders in other fields need to be brought into the TB research fold to generate transformational gains
in basic and clinical research, translation, and implementation. Despite the productivity and accomplishments of
the JHU faculty, nurturing and sustaining a pipeline of New Investigators (NI) who can provide leadership and
innovation in the future is extremely challenging. Without dedicated resources to support NI and ESI, many
trainees move onto other fields. There is a recognized need for seed funding, core resources, and intensive
mentoring for new researchers, who also would benefit from broadened skill sets beyond their primary training.
The DC will seek to draw from areas of underrepresented science and scientists, including opportunities for
future research/training. Fields such as systems biology in TB are lacking; thus, we will seek to bring in
computational modelers, bioinformaticians, and immunologists to fill this void. Novel approaches to
understanding TB pathogenesis are needed, with implications for molecular diagnostics, therapeutic vaccines,
and host-directed therapies. Nursing models to increase prevention, access to treatment, retention and human-
centered adherence models, as well as infection control and prevention science are recognized areas needing
TB outsiders. Finally, engagement of stakeholders in community-based participatory research methods is
increasingly needed in TB control globally.
The overall goals of the JHU TRAC DC are to support the highest priority innovative, cross-disciplinary TB
research, to support and mentor ESI in team science, and to recruit and support NI to TB. Developmental Awards
provided by the DC will provide both ESI and established investigators not currently involved in TB research with
the opportunity to stimulate innovative ideas and to receive support for fruitful new areas of interdisciplinary,
collaborative research. A special focus of the DC will be the recruitment and career development of Investigators
among groups nationally underrepresented in health-related research (UHRR). In addition to the Developmental
Awards, the Developmental Core will augment individual mentorship with Internal Scientific Reviews of grant
proposals, including specific aims reviews; TRAC-specific Writing Accountability Groups (WAGs), a TRAC K-
Club to support development of K01, K08, K23, or K99 applications, and a TRAC K2R Club for investigators
transitioning from K awards to R01 grants. The Developmental Core will work with the Administrative Core to
facilitate exchange of ideas and methodologies through a weekly TRAC Seminar Se...

## Key facts

- **NIH application ID:** 10431022
- **Project number:** 1P30AI168436-01
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** JONATHAN E. GOLUB
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $285,097
- **Award type:** 1
- **Project period:** 2022-03-16 → 2027-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10431022

## Citation

> US National Institutes of Health, RePORTER application 10431022, Developmental Core (1P30AI168436-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10431022. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*