IN-TRAC DEVELOPMENT CORE ABSTRACT The Development Core will establish a culture of continuous education and development for IN-TRAC participants that are new or established new to the TB field. This includes career development training in lab management, grant writing and community engagement, and tailoring the research and clinical experiences to develop TB researchers that are adaptable to the changing landscape of future research and clinical needs. IN- TRAC participants will work within a values-driven, research intensive institute and carefully selected unique, established field sites. The Development Core will award pilot grants to IN-TRAC participants to support multidisciplinary collaborative research, or preliminary and feasibility data for federal and non-federal grant submissions or project development. Specifically, the Development Core proposes: AIM 1: Facilitate multi- disciplinary training experiences for each individual IN-TRAC participant. IN-TRAC participants will accomplish this through intern and extern programs that will introduce them to a spectrum of multifaceted research tools that will be required to address some of the most complex challenges related to understanding, treating or preventing TB. AIM 2: Develop IN-TRAC talent through a program of continuous learning and campus culture. IN-TRAC participants will be exposed to a training program that covers many of the soft skills and intangibles that are needed to develop a highly competitive, collaborative and multidisciplinary research career. AIM 3: Establish a pilot grant program that supports multidisciplinary science. IN-TRAC participants will be eligible for pilot grants to develop independent research programs for their first federal and/or non-federal TB grant applications, to bring new technologies to their laboratories, or to develop collaborative multi-disciplinary programs that will increase opportunities for large programmatic grants related to TB research. At completion, IN-TRAC participants will understand many of the most significant clinical problems for TB detection, surveillance, treatment and prevention. This will be combined with the confidence to move across multiple disciplines and with skills to communicate science effectively to ensure that their TB research is funded, developed, implemented and known worldwide.