# Basic Science Core - Imaging

> **NIH NIH P30** · TEXAS BIOMEDICAL RESEARCH INSTITUTE · 2022 · $199,894

## Abstract

TEXAS BIOMED IN-TRAC Research Imaging Core ABSTRACT
The Research Imaging Core will leverage key strengths of Texas Biomed, namely a strong cohort of NIH-
funded TB investigators with a history of collaboration and with experience in different imaging platforms. IN-
TRAC participants will benefit from access to unique NHP resources in the Southwest National Primate Research
Center (SNPRC) and its cutting edge imaging capabilities. The Research Imaging Core will also establish an
education curriculum to introduce IN-TRAC participants to a variety of cell-based and whole animal imaging
platforms. AIM 1: Provide didactic and hands-on training program in confocal microscopy and optical
imaging. IN-TRAC participants will learn multi-label immunofluorescence or fluorescence in-situ hybridization
(FISH) confocal microscopy, which allows for 3- or 4-D evaluation of tissues and cells with multiple fluorochrome
labels. AIM 2. Provide didactic and hands-on training in cutting-edge cellular immunology techniques
requiring imaging support or computational analysis. The Texas Biomed Biology, Microscopy and Molecular
Cores provide high-dimensional, multi-parameter flow cytometry and analysis as well as BSL3 sorting
capabilities. Established TB researchers will provide training live cell imaging (Cytation 5) and scRNAseq (10x
Genomics) in BSL3. AIM 3: Provide didactic and hands-on training in live imaging using PET/CT and IVIS
systems. Training in whole-body live Positron Emission Tomography (PET) and X-ray Computed Tomography
(CT) imaging of NHP and in-vivo imaging system (IVIS) of rodents within the BSL3. IN-TRAC participants will
extern at the NHP MRI facilities at UTHSCA to learn the advantages and limitations of this imaging platform. At
the completion of the Research Imaging Core, participants will be able to effectively interpret published data that
use imaging modalities for NHP, rodents, tissues, cells and RNA; design experiments to test their own
hypothesis; and participate in TB research that uses the appropriate animal model.

## Key facts

- **NIH application ID:** 10431470
- **Project number:** 1P30AI168439-01
- **Recipient organization:** TEXAS BIOMEDICAL RESEARCH INSTITUTE
- **Principal Investigator:** Deepak Kaushal
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $199,894
- **Award type:** 1
- **Project period:** 2022-03-10 → 2027-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10431470

## Citation

> US National Institutes of Health, RePORTER application 10431470, Basic Science Core - Imaging (1P30AI168439-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10431470. Licensed CC0.

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