# PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAM

> **NIH NIH K12** · BAYLOR COLLEGE OF MEDICINE · 2022 · $745,678

## Abstract

PROJECT SUMMARY/ABSTRACT
This proposal represents the renewal application of the Pediatric Oncology Clinical Research Training Program
(POCRTP), developed by Texas Children’s Cancer Center (TCCC), which is jointly supported by Baylor College
of Medicine’s (BCM) Department of Pediatrics and Texas Children’s Hospital (TCH). The POCRTP is a
comprehensive, multidisciplinary, clinical research education program to train pediatric clinical oncology faculty
to design, implement, conduct, and analyze clinical research trials. Clinical research is essential to advancing
the treatment of childhood cancer; however, clinical fellowships do not provide sufficient training in this area. The
POCRTP emphasizes a team science approach in which laboratory and clinical scientists interact to expedite
the translation of basic research discoveries into clinical therapeutic cancer research. Eligible Scholars must
have completed pediatric hematology-oncology fellowship training and be board-eligible or certified. POCRTP
Scholars receive three years of training that includes core didactics in clinical investigation and trial design and
an in-depth laboratory and clinical research experience focused in one Clinical Research Pathway: Immunology
and Cell Therapy; Genomics and Precision Medicine; or Epidemiology and Survivorship. Scholars are mentored
by both a laboratory and a clinical research mentor, and receive extensive instruction in clinical trial design,
statistical analysis, research ethics, regulatory requirements, scientific writing, grantsmanship, and leadership.
Scholars also participate in BCM’s Institutional Review Board and attend national workshops. Scholars are
expected to publish at least one peer-reviewed manuscript related to their project, develop a peer-reviewed grant
application, and develop and conduct a clinical trial in which they serve as Chair or co-Chair. Since its inception
in 2001, the POCRTP has successfully trained 30 Scholars, the majority of whom are actively involved in
pediatric oncology clinical research. There are currently six Scholars participating in the POCRTP; two Scholars
will complete the Program this summer, and one Scholar will begin in July 2021. For the next funding cycle, we
are proposing several new features to enhance the Scholar’s training and professional development, including
a multi-PI leadership plan whereby Dr. Susan Blaney and Dr. Carl Allen will be co-Leaders of the POCRTP.
Additional features include a formal Research Mentorship Education Program, as well as a required Scholarship
Oversight Committee and formal Individual Development Plan. We are also actively working to enhance the
recruitment of Scholars who are from groups underrepresented in medicine and have recruited additional faculty
mentors to expand the range of scientific expertise, as well as racial and ethnic diversity of the Program.

## Key facts

- **NIH application ID:** 10433766
- **Project number:** 2K12CA090433-21
- **Recipient organization:** BAYLOR COLLEGE OF MEDICINE
- **Principal Investigator:** CARL E ALLEN
- **Activity code:** K12 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $745,678
- **Award type:** 2
- **Project period:** 2002-07-01 → 2027-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10433766

## Citation

> US National Institutes of Health, RePORTER application 10433766, PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAM (2K12CA090433-21). Retrieved via AI Analytics 2026-06-14 from https://api.ai-analytics.org/grant/nih/10433766. Licensed CC0.

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