Project Summary/Abstract An advanced immunoassay system is an essential piece of equipment for clinical pathology laboratories to assess the function and response to injury of various disease conditions but especially hormonal changes and cardiac (heart) conditions. Many food contaminants/misformulations, toxins, microbial agents, cancer and other conditions affect hormone levels and damage the heart These can trigger biochemical changes measured by an immunoassay system. The Oregon Veterinary Diagnostic laboratory (OVDL) has an Immulite system that is now 14 years old, lived its functional life expectancy, breaks down routinely, and is no longer eligible for a service contract and therefore needs to be replaced. The OVDL receives a widely varied diagnostic caseload from domestic animals as well as wildlife, aquatic and marine species of the Pacific Northwest. The OVDL services are vital to a variety of clients and to public health, both of which are key to Vet LIRN’s mission. An advanced and reliable immunoassay system is necessary for the OVDL to be fully operational for Vet LIRN projects and investigations.