# The Center for Accelerating Suicide Prevention in Real-world Settings (ASPIRES)

> **NIH NIH P50** · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · 2022 · $2,858,439

## Abstract

Suicide is a major and growing public health problem among youth in the United States. Integrating suicide
prevention strategies as a core component of health care delivery and providing access to health services for
individuals at risk for suicide is a primary goal of the National Action Alliance for Suicide Prevention (NAASP).
Lack of prevention strategies universally assimilated into routine health care is an obstacle to achieving
meaningful reductions in youth suicide. To address this problem, we propose to develop the Center for
Accelerating Suicide Prevention in Real-world Settings (ASPIRES) to hasten the implementation of effective
and scalable evidence-based interventions to reduce youth suicide. ASPIRES will focus on integrated
programs of research that span the continuum of care from early identification in primary and specialty health
care settings, to acute and transitional care, and back into the community as part of routine health care
practice. The target population is youth at elevated risk for suicide, the majority of which are from lower
socioeconomic households experiencing significant health disparities. The specific aims of ASPIRES include:
(1) Create an infrastructure to foster innovative, transdisciplinary approaches to accelerate the implementation
and utility of youth suicide prevention interventions in real-world settings; (2) Conduct integrated programs of
high-impact research to improve risk detection and deploy innovative interventions that have strong potential
for scalability and sustainability in real-world settings; (3) Characterize the implementation context to generate
recommendations for contextually sensitive implementation strategies for varied healthcare settings; (4)
Cultivate the next generation of emerging and advanced scholars from diverse backgrounds to conduct state-
of-the-art suicide prevention research; (5) Coordinate a program of pilot studies that test the most promising
ideas to accelerate innovations in practice-based youth suicide prevention; and (6) Communicate and
disseminate center-related findings to key stakeholders and promote data sharing. The center’s planned
portfolio of science includes integrated efforts promoting accelerated research across a continuum of health
care settings that could not be accomplished using individual project mechanisms. The signature (R01-level)
hybrid effectiveness-implementation project focuses on universal suicide risk screening and enhancing quality
improvement in pediatric primary care settings. Three exploratory projects include: 1) testing an established
intervention in a specialty care setting to address young children at high familial risk for suicidal behavior; 2)
testing an evidence-based treatment alternative to inpatient hospitalization that targets family functioning to
reduce youth suicidal behavior in an acute care setting; and 3) developing a technology-based intervention to
promote lethal means restriction during the “high-risk” transitional ...

## Key facts

- **NIH application ID:** 10436043
- **Project number:** 1P50MH127476-01A1
- **Recipient organization:** RESEARCH INST NATIONWIDE CHILDREN'S HOSP
- **Principal Investigator:** JEFFREY A BRIDGE
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $2,858,439
- **Award type:** 1
- **Project period:** 2022-08-01 → 2027-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10436043

## Citation

> US National Institutes of Health, RePORTER application 10436043, The Center for Accelerating Suicide Prevention in Real-world Settings (ASPIRES) (1P50MH127476-01A1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10436043. Licensed CC0.

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