# Core 1: Biostatistics and Bioinformatics Core

> **NIH NIH P50** · FRED HUTCHINSON CANCER CENTER · 2022 · $294,623

## Abstract

Project Summary/Abstract – Biostatistics and Bioinformatics Core
The Biostatistics and Bioinformatics Core (BBC) will provide statistical and bioinformatics support for all 
projects within the Core and all SPORE investigators. The Core is comprised of biostatisticians with expertise 
in lung cancer, clinical trials, higher dimensional data processing and analysis, population studies. 
Statistical and bioinformatics leadership ensures that SPORE study design and data analysis yield valid and 
unequivocal answers to hypotheses being tested in projects. BBC faculty and staff will provide statistical 
leadership to all SPORE projects, linking study design, data collection and analysis to scientific goals of the 
SPORE program. The BBC will play an integral role in the collection, quality control, and analysis of data for 
SPORE projects, including career enhancement and developmental research projects (CEP and DRP). It is our 
experience that statistical leadership in research from the concept phase yields studies that are better 
designed, more likely to answer the scientific questions of interest, and more compelling in their conclusions. 
Our scientific projects will require and utilize a variety of assays, including high-throughput and multiparametric technologies, along with cutting-edge computational tools and modeling strategies that can be used 
to analyze and integrate heterogeneous datasets and/or predict responses. Consequently, large-data 
management and computational analysis will be an integral part of this research program. The efficient design 
of clinical trials is also an important component in taking any intervention from bench to bedside. The BCC will 
serve as the quantitative piece of this collaboration by providing experimental and clinical trial design as well as 
analysis and interpretation of data from all experiments and clinical trials that are conducted in the SPORE. 
The Core will be organized around the three aims outlined below, and will directly leverage infrastructures and 
resources already available at the Fred Hutch.

## Key facts

- **NIH application ID:** 10436178
- **Project number:** 5P50CA228944-05
- **Recipient organization:** FRED HUTCHINSON CANCER CENTER
- **Principal Investigator:** Mary W Redman
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $294,623
- **Award type:** 5
- **Project period:** 2019-08-01 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10436178

## Citation

> US National Institutes of Health, RePORTER application 10436178, Core 1: Biostatistics and Bioinformatics Core (5P50CA228944-05). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10436178. Licensed CC0.

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