# Functional genomics resources for the Drosophila and broader research communities

> **NIH NIH P41** · HARVARD MEDICAL SCHOOL · 2022 · $1,356,000

## Abstract

PROJECT SUMMARY – OVERALL
We will build on our existing infrastructure, expertise, and track-record to form the Drosophila Research and
Screening Center-Biomedical Technology Research Resource (DRSC-BTRR). Our overall goal will be to help
researchers realize the full potential of Drosophila as a model for the study of human health and disease, and
as a model of medically-relevant insects such as mosquito vectors of infectious disease. The DRSC-BTRR will
develop state-of-the-art tools and methods in three technology areas: (1) development of functional genomics
technologies for Drosophila cell-based and in vivo studies (including CRISPR-Cas9 technologies); (2)
application of functional genomic and proteomic technologies to mosquito vectors of human diseases; and (3)
development of in vivo proteomics technologies for Drosophila. We will develop the technologies through
iterative rounds of development, testing, and improvement together with a set of driving biomedical projects
that can benefit from application of the technologies. To further extend the impact of the technologies, we will
engage in community activities that inform a broad audience and rapidly disseminate technologies to other
facilities to ensure long-term access. Altogether, we will serve as an integrated, collaborative resource
engaging in projects with strong potential for impact in areas that are of interest to several NIH institutes,
including fundamental cell and organismal biology, developmental biology, cancer therapeutics, rare genetic
disorders, and mosquito-borne diseases.

## Key facts

- **NIH application ID:** 10436790
- **Project number:** 5P41GM132087-04
- **Recipient organization:** HARVARD MEDICAL SCHOOL
- **Principal Investigator:** NORBERT PERRIMON
- **Activity code:** P41 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $1,356,000
- **Award type:** 5
- **Project period:** 2019-08-01 → 2024-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10436790

## Citation

> US National Institutes of Health, RePORTER application 10436790, Functional genomics resources for the Drosophila and broader research communities (5P41GM132087-04). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10436790. Licensed CC0.

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