# NYUCI-ES: Psychosocial Intervention to Improve Health Outcomes for Chinese and Korean ADRD Caregivers

> **NIH NIH P50** · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · 2021 · $733,100

## Abstract

Research Project 3 – NYUCI-ES – Abstract
The physical and emotional demands of dementia caregiving can have enormous negative effects on caregivers’
physical and mental health. Dementia caregivers have increased risk of hypertension and diabetes, compared
to non-caregivers, especially in minority populations. This study will conduct a two-arm randomized controlled
trial to test the efficacy of a culturally tailored version of the NYU Caregiver Intervention (NYUCI) plus enhanced
support (ES) through online chat groups (the NYUCI plus WeChat/Kakaotalk [population social media app for
Chinese/Korean] peer support which we call the NYUCI-ES in reducing health risks for cardiometabolic disease
among older Chinese and Korean-American adults caring for relatives with ADRD. The NYUCI has proven
efficacy in reducing psychological outcomes among largely White samples of caregivers of persons with ADRD
and has been widely replicated and translated in the USA and elsewhere. This study will provide the first large-
scale test of the potential effects of the NYUCI-ES, a multicomponent intervention that includes individual and
family counseling and ongoing support via support group and online chat groups and ad hoc (on demand)
counseling.
 In collaboration with community organizations across the New York and northern New Jersey
metropolitan area, we will enroll 300 caregivers of people with ADRD (150 Chinese and 150 Korean) in this
study. Aim 1: Develop culturally adapted informational and educational materials about dementia and caregiving
issues for social service providers of the intervention and for family caregivers. Aim 2: Test the hypothesis, H1:
A counseling and support intervention (the NYUCI-ES) will significantly improve psychosocial factors such as
depression, stress self-rated health and chronic disease management among Chinese and Korean-American
ADRD caregivers and these changes will be mediated by improvement in social support. H1a: By the first (6-
month) follow-up, the mediators (increases in social support, stress reaction) will improve significantly in the
intervention group compared to baseline values and the control group. H1b: These improvements will be
maintained, and lead to reduction in depressive symptoms, and improvement in self-reported health and chronic
disease self-management by the 12-month follow-up compared to the control group. Aim 3: Test the hypothesis,
H2: the NYUCI-ES will reduce biologic risk factors, including metabolic health (glycosylated hemoglobin) and
inflammation (Oxidative stress, lipid metabolism, etc.) within 6 months of enrollment compared to baseline and
a control group; these changes will be mediated through increases in social support and decreases in depressive
symptoms and will be maintained at the 12-month follow-up.
 The public health significance of these findings will likely have an impact on health care policy for CGs
from diverse underserved ethnic and cultural backgrounds, potentially reducing morb...

## Key facts

- **NIH application ID:** 10437459
- **Project number:** 1P50MD017356-01
- **Recipient organization:** RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS
- **Principal Investigator:** Bei Wu
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $733,100
- **Award type:** 1
- **Project period:** 2021-09-24 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10437459

## Citation

> US National Institutes of Health, RePORTER application 10437459, NYUCI-ES: Psychosocial Intervention to Improve Health Outcomes for Chinese and Korean ADRD Caregivers (1P50MD017356-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10437459. Licensed CC0.

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