# Training Program in Investigative Hepatology

> **NIH NIH T32** · YALE UNIVERSITY · 2022 · $336,182

## Abstract

PROJECT SUMMARY
This proposal is a competitive renewal application for five years of support to continue the 40-year-old Yale
Postdoctoral Training Program in Investigative Hepatology. The goal of this training program is to provide
basic laboratory, translational, or clinical research training for physicians who have completed clinical training
in gastroenterology in preparation for careers as independent investigators in academic hepatology and to
provide research training for recent PhD graduates to prepare them for careers as independent investigators
in basic liver-related research. The program draws on the exceptional liver research environment at Yale,
including a large pool of preceptors who are internationally recognized investigators that are well funded and
have extensive mentorship experience. The program's trainees in turn have a long track record of going on
to become leaders in the field of hepatology; in recent years the majority of trainees have obtained
independent funding, and nearly all have published multiple papers related to their training and have gone on
to academic or other research-intensive careers. The program will continue to train four postdoctoral fellows
at a time, and individual trainees will be supported for two to three years. Selection of trainees will be based
on strong prior research experience and commitment to liver-related research. This training program will use
the combined resources of the NIDDK-funded Yale Liver Center, the Yale Digestive Diseases Section, and
facilities of the participating faculty including the Departments of Internal Medicine, Cell Biology, Cellular and
Molecular Physiology, Human Genetics, Microbial Pathogenesis, Pediatrics, and Pharmacology. The major
research areas represented include (1) liver infection, inflammation, and immunobiology, (2) hepatic
metabolism and steatosis, (3) bile secretion and cholestasis, (4) liver cancer, (5) fibrosis and cirrhosis and (6)
basic liver biology and pathobiology. The Section of Digestive Diseases, the Medical School's Investigative
Medicine Program as well as enrichment programs provided by the Liver Center together provide a strong
and liver-oriented educational curriculum. Trainees are encouraged to audit or enroll in specific courses in the
School of Medicine or the School of Public Health, attend annual laboratory and lecture courses designed for
physician trainees in the Department of Medicine, and are required to attend both Hepatology and Basic
Science Journal Clubs, plus weekly research and pathophysiology seminars. Progress is monitored through
several mechanisms including "Research in Progress" seminars and individual Progress Committees.

## Key facts

- **NIH application ID:** 10437614
- **Project number:** 5T32DK007356-44
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** MICHAEL H NATHANSON
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $336,182
- **Award type:** 5
- **Project period:** 1984-07-01 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10437614

## Citation

> US National Institutes of Health, RePORTER application 10437614, Training Program in Investigative Hepatology (5T32DK007356-44). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10437614. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*