# Core A - Biospecimen Processing.

> **NIH NIH P50** · WASHINGTON UNIVERSITY · 2022 · $186,281

## Abstract

ABSTRACT
The goal of the Biospecimen Processing Core (BPC, Core A) is to provide high-quality, clinically annotated
biospecimens to all five research projects in this SPORE application as well as ongoing and future SPORE-
sponsored DRP and CEP projects, and to serve as an unparalleled biospecimen resource to the broader
cancer research community. The BPC will be responsible for the identification and enrollment of every patient
referred to the Siteman Cancer Center with newly diagnosed and relapsed hematologic malignancy (excluding
multiple myeloma). Biospecimens from these patients will be collected, processed, and stored by leveraging
the extensive infrastructure of the Siteman Cancer Center Tissue Procurement Core (TPC), a CAP-accredited
biorepository with over 15 years of experience in biospecimen banking. Clinical data will be collected
prospectively by integrating with and extending the mission of an existing Clinical Database Core (CDC),
previously established as part of the Genomics of AML (GAML) Program Project to serve as a platform for the
investigation of genetic mutations associated with the pathogenesis of MDS and AML. As such, Core A will
continue to supplement Cancer Center resources with focused expertise and effort to comprehensively collect,
annotate, quality review, and distribute biospecimens specifically for translational leukemia and leukemia-
related cancer research. Specific Aims include:
 Specific Aim 1. To provide expertise in biobanking and clinical annotation to specifically support projects 1-
5 in this SPORE application.
 Specific Aim 2. To provide an on-going, high quality, clinically annotated biospecimen resource of
hematological malignancy patient biospecimens for other translational research projects both within and
external to this SPORE program.
 Specific Aim 3: To create a comprehensive and transparent plan to catalog collected biospecimens and
facilitate their distribution to the broader scientific community of hematologic malignancy investigators.

## Key facts

- **NIH application ID:** 10439619
- **Project number:** 5P50CA171963-10
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** PETER WESTERVELT
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $186,281
- **Award type:** 5
- **Project period:** 2013-09-03 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10439619

## Citation

> US National Institutes of Health, RePORTER application 10439619, Core A - Biospecimen Processing. (5P50CA171963-10). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10439619. Licensed CC0.

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