# Research Training Program in Neuro-Oncology

> **NIH NIH T32** · MAYO CLINIC ROCHESTER · 2022 · $321,308

## Abstract

PROJECT SUMMARY/ABSTRACT
This new T32 Training Grant will contribute knowledgeable and well-trained basic and translational research
scientists experienced in multidisciplinary research in, and informed of the public health importance of, primary
brain tumors, especially gliomas and glioblastoma (GBM) to the nation's cancer research enterprise. A critical
benefit of this process will be an increase in the quality and depth of the translational investigator base in brain
cancer. An equally critical benefit of this process will be the increase in the number of basic and translational
brain tumor research scientists from traditionally underrepresented populations (URP). Each trainee will
develop a skill set of critical thinking, academic rigor and mastery of the experimental technique, all within a
construct of the ethical conduct of research. To meet this objective, the T32 will have: (1) Stringent candidate
selection; (2) Comprehensive guidance by investigators with expertise in the relevant area of interest and
extensive experience as research mentors; (3) Prescribed training and education; and, (4) Collaboration with
investigators within Mayo Clinic Cancer Center (MCCC), its Translational Research Program in Neuro-
Oncology (the Program), and the Mayo Specialized Program of Research Excellence in Brain Cancer (the
SPORE). Except for Year 1, when there will be three trainees, the T32 training cohort will comprise four post-
doctoral trainees yearly for training. Outstanding applicants will be aggressively recruited with efforts especially
directed toward identifying individuals from underrepresented populations. The Mayo Clinic Office for Diversity
and Inclusion will be fully engaged. The T32 will be embedded in a programmatically-based cancer-,
neuroscience-, and neuro-oncology-specific educational environment and an institutional matrix that includes
but is not limited to 12 NIH-funded training grants from 5 institutes, a MCCC K12 physician-scientist training
program, and Career Enhancement Programs of six MCCC SPORE grants. A Center for Clinical and
Translational Science (CCaTS) and the Mayo Clinic Office of Research Postdoctoral Affairs (ORPA) provides
institutional infrastructure to all NIH-funded training and education enterprises including this T32. Each and
every T32 awardee will capitalize on the leverage of numerous strengths present within the Mayo environment.
Brian Patrick O'Neill, MD, (contact) and Richard G. Vile PhD, will be the PI/PDs. Both have the necessary
experience, stature in the field, and seniority to be Training Grant directors. The training faculty comprises 12
Full and 4 Associate Faculty. Each Full Member has a track record of success as a mentor. Each Associate
Member has made a commitment to become a mentor.

## Key facts

- **NIH application ID:** 10440416
- **Project number:** 5T32CA217836-05
- **Recipient organization:** MAYO CLINIC ROCHESTER
- **Principal Investigator:** Brian Patrick O'Neill
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $321,308
- **Award type:** 5
- **Project period:** 2018-08-31 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10440416

## Citation

> US National Institutes of Health, RePORTER application 10440416, Research Training Program in Neuro-Oncology (5T32CA217836-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10440416. Licensed CC0.

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