# LATC Collaborative Projects: Swine Somatic Cell Genome Editing (SCGE) Center

> **NIH NIH U42** · UNIVERSITY OF MISSOURI-COLUMBIA · 2021 · $158,523

## Abstract

Projecty Summary/Abstract
The role of the Genome Editing Testing Section is to validate unique reporter models created by the
Animal Model Production Section and to test novel delivery methods and reagents provided by other
members of the Somatic Cell Genome Editing (SCGE) Consortium. Additionally, the Genome Editing
Testing Section is responsible for creating standard operating procedures (SOPs) and comprehensive
reports for testing new genome editing technologies. The purpose of this proposal is to test the first-
round of reagents that have been proven in the mouse and targeted for evaluation in pigs. In
preparation for translating delivery and editing technologies to the clinic, we aim to complete safety and
efficacy studies in a swine model. Further we will be responsible for preservation of samples from
these studies in anticipation of future needs.

## Key facts

- **NIH application ID:** 10442228
- **Project number:** 3U42OD027090-03S1
- **Recipient organization:** UNIVERSITY OF MISSOURI-COLUMBIA
- **Principal Investigator:** RANDALL S PRATHER
- **Activity code:** U42 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $158,523
- **Award type:** 3
- **Project period:** 2021-08-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10442228

## Citation

> US National Institutes of Health, RePORTER application 10442228, LATC Collaborative Projects: Swine Somatic Cell Genome Editing (SCGE) Center (3U42OD027090-03S1). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10442228. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*