# Core D: Mouse Genetics and Genomics Core

> **NIH NIH P01** · MEDICAL COLLEGE OF WISCONSIN · 2022 · $224,691

## Abstract

Summary/Abstract
All projects in this program will make extensive use of genetically manipulated mice as the primary
experimental platform. The Mouse Genetics and Genomics Core (Core D) is an essential component of the
Program providing critical support to all 4 projects and to scientific cores B and C. The Core will capitalize on
the infrastructure established at the University of Iowa Gene Editing Facility for the generation of genetically
altered mouse models using CRISPR-Cas9 genome editing and in the Genomics Division of the Iowa Institute
of Human Genetics (IIHG) to support genome wide transcriptome analysis. The goals of the Core are to: 1)
provide centralized breeding, genotyping and quality control of transgenic and knockout animals for use by
investigators in the program project, 2) generate new transgenic mouse models needed during the proposed
budget period for Projects 2 and 4 (and in the future for Project 3), and 3) perform and analyze global
transcriptome studies proposed within Projects 1-4.

## Key facts

- **NIH application ID:** 10445016
- **Project number:** 5P01HL084207-15
- **Recipient organization:** MEDICAL COLLEGE OF WISCONSIN
- **Principal Investigator:** ANNE E. KWITEK
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $224,691
- **Award type:** 5
- **Project period:** 2007-06-01 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10445016

## Citation

> US National Institutes of Health, RePORTER application 10445016, Core D: Mouse Genetics and Genomics Core (5P01HL084207-15). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10445016. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*