# Laboratory Animals

> **NIH NIH P30** · THOMAS JEFFERSON UNIVERSITY · 2022 · $132,775

## Abstract

LASR Summary 
The Laboratory Animal Shared Resource (LASR) of the Sidney Kimmel Cancer Center provides technical 
expertise in small animal surgery, administration of chemical carcinogens, imaging, and in-colony health 
surveillance. The LASR also provides housing and quality maintenance and care for laboratory animals used 
by SKCC members using techniques appropriate for cancer research studies. Current goals are to: 1) Support 
the basic research mission of the SKCC by enabling the maintenance, preservation, and dissemination of 
mammalian (primarily mouse) models to provide technical expertise in small animal surgery, administration of 
chemical carcinogens, imaging, and in-colony health surveillance; 2) Consult with and educate investigators 
and their laboratory members on study design and genetic/genomic approaches; 3) Provide a centralized, 
state-of-the art service for cryopreservation of mouse germplasm to preserve useful mouse models; 4) Provide 
high-quality and affordable care of animals used in cancer research; 5) Provide housing and quality 
maintenance and care for laboratory animals used by SKCC staff. The services provided by the LASR are 
crucial for the cancer research performed by SKCC members and continue to evolve with changing research 
needs. Drs. Siracusa and Daviau keep abreast of new developments and methodologies to improve the 
efficiency and cost-effectiveness of all services. Future LASR goals include: 1) Develop gene-editing 
technologies such as CRISPR/Cas9 to generate relevant mouse models of cancer; 2) Enhance lab animal 
facility to address needs of the expanding center; 3) Assist investigators in developing and maintaining PDX 
models of disease.

## Key facts

- **NIH application ID:** 10447607
- **Project number:** 5P30CA056036-23
- **Recipient organization:** THOMAS JEFFERSON UNIVERSITY
- **Principal Investigator:** Luis J Sigal
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $132,775
- **Award type:** 5
- **Project period:** 1995-06-22 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10447607

## Citation

> US National Institutes of Health, RePORTER application 10447607, Laboratory Animals (5P30CA056036-23). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10447607. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*