Project summary/abstract (Overall) The state of Pennsylvania and its associated GenomeTrakr network has consistently met all obligations of the Food and Drug Administration’s program since joining in 2016. The required personnel have worked seamlessly together, and effective standard operating procedures have led to the uploading of over 2,000 quality genomes and associated metadata to public databases. For this next funding cycle, we will continue this trajectory while looking for opportunities to expand our impact within the Commonwealth, particularly with the Pennsylvania Department of Agriculture. We will additionally expand our international reach to further diversify collections submitted to the Pathogen Detection database and to provide isolates for sequencing by other GenomeTrakr partners.