# Biostatistics and Bioinformatics

> **NIH NIH P50** · DANA-FARBER CANCER INST · 2022 · $196,689

## Abstract

PROJECT SUMMARY 
The purpose of the Biostatistics and Bioinformatics Shared Resource Core 2 is to provide consultation and 
collaboration on quantitative methods on all SPORE Projects, Developmental Projects, and Admin Core and 
Shared Resource Core 1. Successful collaboration between the project leaders and the biostatisticians and 
computational biologists in this SPORE, as well as members of the other Cores, is essential to achieve the 
goals of the projects. Members of this core will provide support for the design, analysis, and reporting of 
laboratory, animal, translational, genomic, and clinical studies. Depending on the project, these collaborations 
could range from short consultations to large collaborative projects, and will include assistance in preparation of 
grant applications and manuscripts related to the SPORE projects. The Core members will also provide 
statistical and bioinformatics mentoring to the researchers, with a particular emphasis on Career Development 
Awardees and Developmental Project Investigators. Important for the success of the SPORE is the coordination 
of data management and quality control procedures. The biostatisticians and computational biologists are an 
integral part of this process at the DFCI, and will continue to provide input on the existing procedures, as well as 
recommendations on additional computational infrastructure, which might be necessary for this SPORE. To 
achieve the goals of the SPORE, we propose the following specific aims: 
Specific Aim 1. To provide computational biology and bioinformatics collaboration for SPORE Projects, 
Developmental Projects, and Cores. This includes design, preprocessing, storage, and analysis of all high 
throughput genomic studies. 
Specific Aim 2. To provide biostatistical collaboration for SPORE Projects, Developmental Projects, and 
Cores. This includes design, conduct, analysis and reporting of laboratory and clinical protocols; including the 
coordination of laboratory results with patient characteristics and outcomes from the clinical studies. 
Specific Aim 3. To provide consulting and statistical education to SPORE researchers. To foster rigor and 
reproducibility of all computational activities in the SPORE, the core will also provide or recommend supporting 
computational infrastructure for data collection, form development, data processing, and quality assurance of 
clinical trials data, as well as moving data between databases for laboratory, animal, and relevant clinical studies.

## Key facts

- **NIH application ID:** 10449083
- **Project number:** 5P50CA100707-19
- **Recipient organization:** DANA-FARBER CANCER INST
- **Principal Investigator:** Giovanni Luigi PARMIGIANI
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $196,689
- **Award type:** 5
- **Project period:** 2003-09-16 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10449083

## Citation

> US National Institutes of Health, RePORTER application 10449083, Biostatistics and Bioinformatics (5P50CA100707-19). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10449083. Licensed CC0.

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