# Oklahoma Center for Respiratory and Infectious Diseases

> **NIH NIH P20** · OKLAHOMA STATE UNIVERSITY STILLWATER · 2022 · $2,236,246

## Abstract

PROJECT SUMMARY
 This CoBRE Phase II application seeks support to further develop the multi-institute Oklahoma Center
for Respiratory and Infectious Diseases (OCRID) into a sustainable center of research excellence. Established
in 2013 through the Phase I CoBRE grant, OCRID is quickly becoming a focal point for expanding respiratory
infectious disease research in Oklahoma. OCRID investigators come from major research institutions across
the state of Oklahoma, including 10 colleges at Oklahoma State University (OSU) and the University of
Oklahoma (OU), as well as an independent research institute, the Oklahoma Medical Research Foundation
(OMRF). OCRID is unified by a commitment to excellence in research and training in respiratory and infectious
diseases. Our scientists and leadership cultivate excellence through deliberate faculty mentorship, robust
interdisciplinary collaboration, innovative research, and a dynamic bench-to-bedside-to-marketplace approach.
As the first CoBRE grant ever received by OSU, the Phase I award has made a transformative change in the
research landscape on respiratory infectious disease research in Oklahoma. Building on the success of the
Phase I award, the overall objective of this Phase II CoBRE application is to build a sustainable research
center of excellence in the field of respiratory and infectious diseases. Of the four Phase II research projects on
respiratory infectious diseases in this application led by four talented and promising junior investigators, two
focus on influenza virus, one on Streptococcus pneumonia and one on Pseudomonas aeruginosa. Aim 1 will
expand the critical mass of multi-disciplinary investigators in the thematic area of respiratory infectious
diseases. This aim will be accomplished by 1) mentoring four Phase II project leaders to become NIH-funded
independent investigators; 2) hiring at least 4 new tenure-track faculty members whose research is within the
focus of the Center; 3) nurturing junior investigators and re-directing established investigators into respiratory
infectious disease research via a pilot project program; and 4) recruiting and mentoring replacement project
leaders after the current Phase II project leaders rotate out after the initial 2-3 years of support. Aim 2 will
further develop the research infrastructure by strengthening three unique research cores (Animal Models,
Immunopathology, and Molecular Biology). Aim 3 will enhance inter-institutional collaborations in Oklahoma to
develop a self-sustainable respiratory and infectious research center. The further development of OCRID via
this Phase II CoBRE will have even greater positive impact on respiratory and infectious disease research in
the state of Oklahoma and will sustain the only Center of its kind in Oklahoma.

## Key facts

- **NIH application ID:** 10459258
- **Project number:** 5P20GM103648-10
- **Recipient organization:** OKLAHOMA STATE UNIVERSITY STILLWATER
- **Principal Investigator:** LIN LIU
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $2,236,246
- **Award type:** 5
- **Project period:** 2013-07-01 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10459258

## Citation

> US National Institutes of Health, RePORTER application 10459258, Oklahoma Center for Respiratory and Infectious Diseases (5P20GM103648-10). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10459258. Licensed CC0.

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