# Integrated Technologies

> **NIH NIH P30** · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · 2022 · $1,033,124

## Abstract

Abstract - Integrated Technologies Core 
The overall goal of the Integrated Technologies Core (ITC) is to provide coordinated access and cost-effective 
support for our facility – the Center for Biomolecular Structure (CBMS). 
The first role of the ITC within the CBMS is to enable technical and engineering support for two of the three 
scientific technical cores; these two cores are the ones that depend on hard-x-ray diffraction, two 
Macromolecular Crystallography (MX) beamlines: Frontier Microfocus Macromolecular Crystallography 
(FMX), and Highly Automated Macromolecular Crystallography (AMX), and scattering: Life Science X-ray 
Scattering (LiX), in structural biological studies. Constructed predominantly with an award from the 
National Institutes of Health (NIH), these three beamlines support structural biology and other disciplines, 
and the funding in this grant will support their continued operation. The third technical core, the Imaging 
core, serves five beamlines built and operated mostly by the Department of Energy (DOE) Basic Energy 
Sciences (BES), for which the life-science studies that we will support on these beamlines represent a minor 
component of their entire programs. Therefore, the maintenance and upgrade role that the ITC plays for the 
MX and Scattering Cores will be played by existing BES-sponsored technical staff for the Bioimaging Core. 
The second function of the ITC is to coordinate standards for hardware, software, controls, and networking 
and computing systems. It also assures resource sharing among all scientific technical cores in CBMS and 
supports efficient communication with the National Synchrotron Light Source II (NSLS-II) beamlines and 
the technical and engineering groups. 
We believe that by organizing our technical staff to function across the three beamlines we will make better 
use of our resources. We estimate that our collaboration saves personnel resources equivalent to two to three 
FTE. By pooling spare parts, and assuming equipment failures to be random, for three beamlines the 
reduction in investment in spares amounts to approximately 40%. This will allow us to provide backup 
coverage and extra support among the three, to be consistent in instrument design, and to make efficient 
use of accepted facilities-maintenance standards. Numerous resources within the ITC exist also in the rest 
of the NSLS-II; for us to share and exchange knowledge and apparatus will cross-fertilize opportunities for 
all of us and foster greater efficiency.

## Key facts

- **NIH application ID:** 10460484
- **Project number:** 5P30GM133893-04
- **Recipient organization:** BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB
- **Principal Investigator:** Martin Fuchs
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $1,033,124
- **Award type:** 5
- **Project period:** 2019-09-01 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10460484

## Citation

> US National Institutes of Health, RePORTER application 10460484, Integrated Technologies (5P30GM133893-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10460484. Licensed CC0.

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