Abstract The applicant proposes the continued development and expansion of a successful research education program for graduate level students and professionals to acquire innovative research skills to address drug abuse and related behavioral health concerns of children and adolescents with an emphasis in implementation science. We continue our effort of addressing research education that target minorities and under-represented groups of researchers with interests in working with high risk populations including children and families of AI descent and Hispanic populations with substance abuse and other co-morbid behavioral health conditions. We continue to innovate through the utilization of Peer Mentors who are provided advanced research education opportunities in research project leadership. Implementation Science continues to be at the forefront of innovative research education; the Institute for Translational Research and Education in Adolescent Drug Abuse (ITRE) is unique in focusing on training in implementation research methods, with practical applications in programs at the community level. We emphasize translation of implementation research into community practice and the practical skills of participatory research. A cross-disciplinary approach, involving multiple colleges at the University of South Florida and Northern Arizona University, as well as local community service agencies, has been developed with special attention to evidence-based practice, translational research, and children and adolescents from high risk, marginalized populations.