# Admin Core

> **NIH NIH U19** · BOSTON UNIVERSITY MEDICAL CAMPUS · 2022 · $574,217

## Abstract

The mission of the Framingham Heart Study–Brain Aging Program (FHS-BAP) is to conduct, facilitate and
promote high impact research on the etiology, pathogenesis, diagnosis, treatment, and prevention of Alzheimer
disease (AD) and related disorders. The Administrative Core serves as a focal organizational point to organize
and harmonize research activities of the Clinical, Neuropsychology, and Data Cores and Projects 1-3 to
maximize synergy, efficiency and productivity. In the proposed funding period, the Administrative Core will guide
the extension and expansion of the rich FHS data resource and establish a management infrastructure that will
greatly increase the sharing and utilization of this resource by other researchers worldwide. To accomplish these
central goals, the Administrative Core will serve as the interface between internal FHS-BAP activities and
external entities, and ensure that FHS-BAP activities meet all Core and project milestones and are consistent
with the National Institute of Aging (NIA) AD research mission and in full compliance with all human subjects,
and scientific integrity policy requirements of the NIH. We will form an External Advisory Committee (EAC) to
advise on the formulation and execution of FHS-BAP priorities and proactively identify opportunities that will
keep us on the forefront of forward-thinking science. Key to executing the Administrative Core's mission is to
provide appropriate financial oversight of the entire FHS-BAP, track the disposition of materials provided and
the outcomes of FHS-BAP supported research (publications and funded activities) and present progress in
meeting the stated aims to the EAC feedback will be critical in assessing effectiveness of operational activities
in meeting research priorities and their oversight and continuous input for improvements help ensure we achieve
our stated goals. Additionally, consideration and coordination of FHS-BAP day-to-day operations with other FHS
research programs (e.g., NHLBI funded FHS contract to support core health exams of FHS cohorts) and other
ancillary studies that are collecting data from FHS participants at the FHS clinic based in Framingham, MA will
be done in collaboration with an Internal Advisory Board (IAB), consisting of locally based BU faculty to better
address time-sensitive logistical issues. The Administrative Core will also promote new innovative AD research
using data generated by the FHS-BAP through a pilot project program that will encourage grant applications
from junior faculty and postdoctoral fellows, as well as from established faculty who are new to the AD field,
throughout BU and possibly other institutions. Additional efforts to foster innovative AD research will be
facilitating cross-core/project interactions by promotion of collaborations between FHS-BAP investigators with
local, national, and international research programs, by representing the FHS-BAP at scientific meetings and
publicizing FHS-BAP data access and u...

## Key facts

- **NIH application ID:** 10468280
- **Project number:** 5U19AG068753-03
- **Recipient organization:** BOSTON UNIVERSITY MEDICAL CAMPUS
- **Principal Investigator:** Lindsay A. Farrer
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $574,217
- **Award type:** 5
- **Project period:** 2020-09-15 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10468280

## Citation

> US National Institutes of Health, RePORTER application 10468280, Admin Core (5U19AG068753-03). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10468280. Licensed CC0.

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