# RL5: Research Education Core

> **NIH NIH P30** · BOSTON UNIVERSITY MEDICAL CAMPUS · 2022 · $133,125

## Abstract

Summary/Abstract
Research Education Component (REC) Program
A major research focus of the BU ADRC is to conduct cutting edge research on Alzheimer's
disease (AD) and AD related dementias (ADRD), including chronic traumatic encephalopathy
(CTE), with special attention to identifying the differences and similarities between groups,
leveraging the BU ADRC's data-rich environment featuring access to world-class cohorts such
as the Framingham Heart Study, the DIAGNOSE CTE Study, next-generation digital and
biomarker datasets, as well as diverse and inclusive research populations found in the BU
ADRC's Hope Study. The REC will use the unique expertise of the BU ADRC and affiliated
faculty to provide advanced research training as it relates to common themes of
neurodegeneration in AD/ADRD and related investigative treatments. The REC program goals
are: (1) to maintain 4 postdoctoral/early-career trainees for 2-year terms among 3 different
tracks: (a) a basic science track; (b) a clinical science track; and (c) a data management and
biostatistics track; (2) to ensure at least half of REC trainees are underrepresented groups and
(3) to enable trainees to transition to independence. The scientific and research training of the
REC will be focused on (1) AD, including its pathology, pathophysiology, risk factors, genetics,
biomarkers, clinical symptoms, and behavioral manifestations, and (2) common and distinct
themes related to neurodegeneration, including how pathology, pathophysiology, risk factors,
genetics, biomarkers, clinical symptoms, and behavioral manifestations of AD compare and
contrast to other ADRD.
The BU ADRC REC is committed to developing a diverse cohort of independent AD/ADRD
researchers from advanced trainees and early-career faculty, savvy in working across rich
cohort studies to unlock central mechanisms in the detection and treatment of dementia. We will
achieve this objective, and serve the other Cores in this application, by providing didactic and
practical training in essential basic and translational research and clinical fundamentals of
AD/ADRD, training in research fundamentals and critical professional skills, with an emphasis
on the responsible conduct of research with animal and human subjects, and diverse and
vulnerable populations, and high quality, individualized, detailed mentorship to prepare a
diverse cohort of trainees for independent investigator status in AD/ADRD research.

## Key facts

- **NIH application ID:** 10468313
- **Project number:** 5P30AG072978-02
- **Recipient organization:** BOSTON UNIVERSITY MEDICAL CAMPUS
- **Principal Investigator:** Maureen Katheleen O'Connor
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $133,125
- **Award type:** 5
- **Project period:** 2021-08-15 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10468313

## Citation

> US National Institutes of Health, RePORTER application 10468313, RL5: Research Education Core (5P30AG072978-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10468313. Licensed CC0.

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