SUMMARY Since 2004, Vasculata conferences have been convening across various academic institutions. This conference falls under the auspices of the North American Vascular Biology Organization (NAVBO), and the NAVBO Education Committee selects the hosting site for each year. At their last meeting, the committee chose Duke University School of Medicine (Duke) as the host of the 2022 meeting in the Triangle area with participation by faculty from Duke and UNC at Chapel Hill. This meeting has steadily grown over the years to 120 attendees. Vasculata is an intense “boot camp” that introduces students and fellows to vascular biology. Emphasis of the host site (Duke/UNC) is on short seminars covering a defined curriculum and reading assignments in the original literature. Contact with local faculty and fellows, including within workshops and poster sessions, is a critical aspect of the course. The meeting will focus on environmental and gender modifiers of vascular health and will introduce the local academic environment, especially vascular biology and hematology minded researchers, to the scientific community of the Triangle area. Duke University, University of North Carolina at Chapel Hill, and NIEHS have a rich history of cardiovascular research and at this meeting will disseminate their knowledge and expertise to the community. Training next generation scientists and underrepresented minorities in vascular research is a key objective, and will be facilitated at this conference. Researchers from the Research Triangle North Carolina area study a variety of topics including microcirculation, vascular tone, vascular integrity, pediatric pulmonary circulation, congenital heart defect, blood- vascular interface, immune-vascular interface, bleeding disorders, redox biology and hypertension-related research. All these topics are of interest and directly relevant to NHLBI mission. Further, training, dissemination of new knowledge through workshops and presentations, and providing career-related information to a diverse pool of trainees fit with the education mission of NHLBI.