# Cancer Biostatistics Shared Resource

> **NIH NIH P30** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2022 · $226,309

## Abstract

CANCER BIOSTATISTICS SHARED RESOURCE: PROJECT SUMMARY
The Cancer Biostatistics Shared Resource (CBSR) provides essential capabilities and infrastructure in
support of Herbert Irving Comprehensive Cancer Center (HICCC) members by providing statistical expertise
to basic and clinical researchers who are conceptualizing and developing research projects and clinical trials.
The CBSR offers a wide range of services including (1) summarizing statistical considerations for grant
applications and scientific publication such as power analyses, forms creation, measures specifications, and
simple consultations on study design and biostatistics analyses; (2) identifying and defining outcome variables
and covariates; (3) analyzing expected effect sizes; (4) designing stratification and randomization schemes;
(5) designing human study-specific features such as stopping rules for toxicity; and (6) interim analysis
procedures for efficacy, futility, and blinding. In these functions the CBSR assists HICCC members by
ensuring data rigor and reproducibility; providing descriptive and summary statistics in the form of tables,
charts, and graphs; conducting specified as well as ancillary and exploratory analyses; assisting with
manuscript preparation; and reviewing completed studies for accurate reporting and proper interpretation of
results. The CBSR has been completely restructured following the recruitment of Jianhua Hu, PhD, as CBSR
Director in 2018 and now provides a comprehensive, accessible, cost-effective, and well-structured array of
services to HICCC members. Because of unique expertise, costly computational infrastructure, and complex
analytics requiring direct interaction and high accessibility, the CBSR services cannot be effectively accessed
commercially or via external academic units. In addition to analytical services, the CBSR also provides training
to HICCC members and serves as an educational resource for the HICCC. The CBSR has developed
standardized operating procedures for data handling, management, analysis, and reporting to ensure
completeness and appropriateness of analytic procedures, safeguarding the highest standards in rigor and
reproducibility. The CBSR will continue to develop and incorporate new analytical and statistical methodology
into the services offered in order to provide accessible, high-quality, and affordable statistical services to basic
and clinical investigators in the HICCC, advancing the rigor, reproducibility, and value of the HICCC Research
Programs. Since the recruitment of Dr. Hu as Director, the CBSR has been utilized by 36 HICCC members,
supported multiple pilot grants, and serves an NCI funded P01 and two NCI SPOREs under review.

## Key facts

- **NIH application ID:** 10469540
- **Project number:** 5P30CA013696-47
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Jianhua Hu
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $226,309
- **Award type:** 5
- **Project period:** 1997-07-04 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10469540

## Citation

> US National Institutes of Health, RePORTER application 10469540, Cancer Biostatistics Shared Resource (5P30CA013696-47). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10469540. Licensed CC0.

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