# Clinical Data and Informatics Core

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2022 · $235,990

## Abstract

PROJECT SUMMARY/ABSTRACT – Clinical Data and Informatics Core
The Clinical Data and Informatics Core (CDI) Core will provide researchers with access to a full range of services
to facilitate successful use of clinical data for basic, clinical and translational research studies in rheumatic
diseases. The Core will streamline clinical research infrastructure, including study design, research ethics
consultation, patient recruitment, clinical informatics and disease expertise, to advance precision medicine in
rheumatic disease. We propose the following Aims for the CDI Core: 1) To facilitate use of unique clinical study
databases and biospecimens, 2) To provide individualized consultative services to assist in the design,
implementation and analyses of clinical and translational research studies of rheumatic disease, 3) To provide
clinical informatics services and innovations that accelerate the science and operations of clinical and
translational research, and 4) To contribute clinical data assets in the CDI Core into the integrated UCSF Data
Library that includes the Genomic Technology and Integrated Bioinformatics Cores. Advancing precision
medicine in rheumatic diseases will require a patient-oriented approach that optimizes coordination of these
highly specialized resources across projects. Key strengths of the Core include internationally renowned clinical
experts in rheumatology, national leaders in clinical research and clinical informatics, and expertise in human
subjects research ethics. Core services will continue to address some of the challenges facing the research
community studying rheumatic diseases. These include the need for well-phenotyped patients with high-quality
clinical data with linked biospecimens for rheumatic conditions such as systemic lupus erythematosus, vasculitis,
spondyloarthritis and others; the need to more efficiently identify and recruit patients for clinical studies using
innovative tools linked to electronic health records (EHRs), particularly those with uncommon diseases or clinical
phenotypes; and the current lack of coordination of research infrastructure across ongoing studies, leading to
inefficiencies in patient recruitment, data collection, and data management. Innovations of the CDI Core include
leveraging robust existing clinical informatics infrastructure to bridge the divide between the vast amount of
accumulating clinical data and individual investigators who are interested in specific clinical rheumatic diseases;
developing and disseminating tools for the more efficient and valid use of EHR data for research; and
development of educational modules to accelerate knowledge acquisition among the research community. The
overall goal of these activities is to provide critical and cutting-edge resources that create economies of scale for
researchers at UCSF and nationally conducting clinical research in the rheumatic diseases.

## Key facts

- **NIH application ID:** 10469676
- **Project number:** 5P30AR070155-07
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** Jinoos Yazdany
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $235,990
- **Award type:** 5
- **Project period:** 2016-09-21 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10469676

## Citation

> US National Institutes of Health, RePORTER application 10469676, Clinical Data and Informatics Core (5P30AR070155-07). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10469676. Licensed CC0.

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