# Training Program in Free Radical and Radiation Biology

> **NIH NIH T32** · UNIVERSITY OF IOWA · 2022 · $323,222

## Abstract

Project Summary/Abstract:
The Free Radical and Radiation Biology Training Program in the Department of Radiation Oncology and the
Holden Comprehensive Cancer Center was established in 1998 to provide interdisciplinary graduate and post-
graduate training with a focus on six goals including: 1) Impart a fundamental understanding of radiation
biology, free radical biology, and cancer biology; 2) Provide opportunities to achieve excellence in experimental
radiation biology, free radical biology, and molecular oncology; 3) Provide trainees with skills in hypothesis
driven research, execution of rigorous experimental designs, and rigorous evaluation of scientific results for
peer-reviewed publication; 4) Offer real-world experiences in collaborative basic and translational research
involving both clinical and basic science faculty to facilitate the movement of knowledge in free radical and
radiation biology from the bench-to-bedside; 5) Provide trainees with the critical thinking skills necessary to
effectively communicate scientific knowledge in both oral and written presentations; and 6) Encourage trainees
to pursue innovative approaches to test basic mechanisms underlying radiobiology and redox cancer biology
emphasizing the development of novel interventions to limit the health impact of cancer.
 We are proposing to support three predoctoral and three postdoctoral trainees per year. We have an
internationally recognized faculty with a consistent track record of success in peer reviewed funded
research/publications in radiobiology, redox biology, and cancer biology. We propose to have 26 well-funded
and dedicated program faculty members (both junior and senior faculty) embracing a diverse knowledge base
that synergistically integrates both the interdisciplinary graduate programs in Free Radical and Radiation
Biology as well as Cancer Biology in the Biomedical Sciences Umbrella program at the University of Iowa. The
26 program faculty members consist of 15 Professors, 8 Associate Professors, and 3 Assistant Professors of
which 5 are from Radiation Oncology, 3 from Surgery, 5 from Internal Medicine, 3 from Biochemistry, 2 from
Pharmacology, 2 from Anatomy and Cell Biology, 3 from Pediatrics and 1 each from Microbiology/Immunology,
Radiology, and Molecular Physiology and Biophysics. Educational activities include one-on-one mentoring by
faculty, cancer-related nationally recognized research projects, presenting work and receiving feedback at
national meetings, 2 program specific journal clubs/week, 1 seminar/week, 1 translational research
meeting/week, and technical training in the state of-the-art Radiation and Free Radical Research core lab
based in the program. Formal graduate level coursework includes classes in radiation, redox, and cancer
biology as well as a course in medical physics with an emphasis on image guided cancer therapy. The
interdisciplinary cancer related research being pursued by the faculty spans a wide spectrum from basic
mechan...

## Key facts

- **NIH application ID:** 10473696
- **Project number:** 5T32CA078586-23
- **Recipient organization:** UNIVERSITY OF IOWA
- **Principal Investigator:** Douglas Robert Spitz
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $323,222
- **Award type:** 5
- **Project period:** 1999-07-01 → 2025-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10473696

## Citation

> US National Institutes of Health, RePORTER application 10473696, Training Program in Free Radical and Radiation Biology (5T32CA078586-23). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10473696. Licensed CC0.

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