# Core D: Biostatistics Core

> **NIH NIH P01** · WEILL MEDICAL COLL OF CORNELL UNIV · 2022 · $92,679

## Abstract

BIOSTATISTICS CORE SUMMARY
The Weill Cornell Medicine and The Ohio State University Mechanism-Based Targeting of Mantle Cell
Lymphoma Program Project Grant Biostatistics Core consists of two highly experienced biostatisticians who
will dedicate efforts to support all projects and cores that comprise this grant application. The core aims to
provide long-term collaborative support to the three major projects and also to work closely with members of
the other cores and provide them with needed biostatistical support. Specifically, the Biostatistics Core will
collaborate with investigators on study design, conduct, data collection and management, and analysis plans
for laboratory and animal studies (aim 1), clinical studies (aim 2), and profiling studies (aim 3), including
experimental design, sample size and power calculations, assessment of feasibility, application of appropriate
statistical analysis techniques, and summarization of findings. The biostatistical support on high-dimensional
data analysis with each project will be provided through a close and synergistic relationship with the Genomics
& Bioinformatics Core. In addition, core members will monitor the research progress, will provide a centralized
repository for data generated from P01 projects and cores, will standardize data collection across the projects
and core, will perform quality checks on data, and will develop novel statistical methods if emerging statistical
issues from the P01 projects require so. The Biostatistics Core will play a key role in facilitating synergies
across the projects and core through the sharing of data, results, and lessons learned.
Through the already existing interaction with the project leaders, core members have co-authored several
publications related to Mantle Cell Lymphoma. There is also an established collaborative partnership between
members of the Biostatistics and Genomics & Bioinformatics Cores with respect to the analysis of high-
dimensional genetic, genomic, epigenetic, and proteomic data. In conjunction with the Administrative Core, the
Pathology Core, and the Genomics & Bioinformatics Core, we will ensure all the projects progress as planned,
and the results are accurate and reliable.
!

## Key facts

- **NIH application ID:** 10478992
- **Project number:** 5P01CA214274-05
- **Recipient organization:** WEILL MEDICAL COLL OF CORNELL UNIV
- **Principal Investigator:** Karla V. Ballman
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $92,679
- **Award type:** 5
- **Project period:** 2018-09-18 → 2025-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10478992

## Citation

> US National Institutes of Health, RePORTER application 10478992, Core D: Biostatistics Core (5P01CA214274-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10478992. Licensed CC0.

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