# Novel Wiring Catheter for Crossing Complex Chronic Total Occlusions

> **NIH NIH R43** · MINNESOTA HEALTHSOLUTIONS CORPORATION · 2022 · $299,975

## Abstract

Project Summary/Abstract
We propose to develop an innovative wiring catheter system to reliably direct subintimal crossing and re-entry
into the artery true lumen during treatment of complex arterial chronic total occlusions (CTO). The proposed
system will improve techniques for treating complex CTOs during percutaneous coronary and peripheral artery
interventions (PCI). Atherosclerosis drives development of coronary artery, cerebrovascular, and peripheral
arterial disease. Improved CTO crossing devices and techniques will allow more operators to perform these
procedures and improve patient care. The proposed project investigates key elements of a novel guided re-entry
catheter system to be used in a rendezvous maneuver to increase the precision, speed, reliability, and safety of
retrograde CTO PCI crossing. A prototype device will be developed and evaluated.

## Key facts

- **NIH application ID:** 10483058
- **Project number:** 1R43HL164194-01
- **Recipient organization:** MINNESOTA HEALTHSOLUTIONS CORPORATION
- **Principal Investigator:** Nick Rydberg
- **Activity code:** R43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $299,975
- **Award type:** 1
- **Project period:** 2022-04-01 → 2025-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10483058

## Citation

> US National Institutes of Health, RePORTER application 10483058, Novel Wiring Catheter for Crossing Complex Chronic Total Occlusions (1R43HL164194-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10483058. Licensed CC0.

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