# Immune Regulation of Gastric Cancer

> **NIH NIH P20** · WEST VIRGINIA UNIVERSITY · 2021 · $269,225

## Abstract

Gastric cancer is the 3rd leading cause of cancer deaths worldwide. Over 90% of gastric cancers are associated with long-term Helicobacter pylori infection. However, the infection alone has limited pathogenic effects on the gastric mucosa. Rather, the infection triggers massive gastric inflammation, which becomes increasingly hyperactive, damaging the stomach and creating the requisite environment for carcinogenesis. However, the mechanisms and pathways that regulate the onset of hyperactive inflammation are unknown.

## Key facts

- **NIH application ID:** 10485122
- **Project number:** 5P20GM121322-04
- **Recipient organization:** WEST VIRGINIA UNIVERSITY
- **Principal Investigator:** Jonathan Busada
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $269,225
- **Award type:** 5
- **Project period:** 2021-07-01 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10485122

## Citation

> US National Institutes of Health, RePORTER application 10485122, Immune Regulation of Gastric Cancer (5P20GM121322-04). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10485122. Licensed CC0.

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