# Administrative Core

> **NIH NIH U2C** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2022 · $91,088

## Abstract

The development and validation of biomarkers for the early detection of cancer requires a team
of investigators and resources to move from discovery through stages of validation to the ultimate
goal of a clinically approved and useful test. This Biomarker Characterization Center proposes
to develop and validate blood-based cancer specific DNA methylation biomarkers by bringing
together investigative teams from three NCI designated Comprehensive Cancer Centers (The
UMPC Hillman Comprehensive Cancer Center at the University of Pittsburgh, The Sidney Kimmel
Comprehensive Cancer Center at Johns Hopkins, and The University of Maryland Marlene &
Stewart Greenebaum Comprehensive Cancer Center) to accomplish this complex task. To
coordinate and support these efforts, an administrative core will integrate activities of EDRN BCC
investigators. The administrative core of this Biomarker Characterization Center oversees,
coordinates and supports the activities of this multidisciplinary program. Through overseeing and
supporting these activities, the individual components of the Biomarker Development Laboratory
and the Biomarker Reference Laboratory are able to effectively accomplish their objectives and
integrate their activities with other components of the BCC (BDL and BRL), with other NCI
programs and with other EDRN centers (BCCs, CVCs and the DMCC).

## Key facts

- **NIH application ID:** 10486259
- **Project number:** 1U2CCA271885-01
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** JAMES G. HERMAN
- **Activity code:** U2C (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $91,088
- **Award type:** 1
- **Project period:** 2022-09-16 → 2027-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10486259

## Citation

> US National Institutes of Health, RePORTER application 10486259, Administrative Core (1U2CCA271885-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10486259. Licensed CC0.

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