# Microbial Genomics and Analytical Laboratory (M-GAL)

> **NIH NIH P20** · UNIVERSITY OF HAWAII AT MANOA · 2022 · $140,773

## Abstract

Project Summary – CORE C: Microbial Genomics and Analytical Laboratory (M-GAL) 
The Microbial Genomics and Analytical Laboratory (M-GAL) Core of the Integrative Center for Environmental 
Microbiomes and Human Health will provide a centralized facility and technical expertise at the University of 
Hawai`i at Mānoa (UHM) to support the study of the interface between the microbial environment and human 
health. The characterization of microbial community composition by next-generation sequencing and analysis 
of microbial metabolic products are standard methods used in the field of microbiome research. To enable 
these applications, the M-GAL Core will provide the following: (i) equipment and expertise for the preparation 
of genomic libraries and the quantitation of gene expression; (ii) high-performance liquid chromatography and 
mass spectrometry instrumentation for the analysis of lipids and metabolites; (iii) facilities for the cultivation, 
isolation, and long-term storage of microbial strains; and (iv) curation of a community searchable database 
containing information about strains isolated from native Hawaiian fauna and ecosystems. The M-GAL core 
will be available to researchers throughout the state of Hawai'i and visiting scientists, thus encouraging greater 
interaction amongst the local microbiome research community and seeding collaborative efforts from abroad. 
The M-GAL Core will beneficially impact COBRE investigators and affiliates by providing essential 
infrastructure and expertise to advance their research and foster the careers of junior faculty. Moreover, the 
Core will support the growth of UHM as a major center for microbiome studies in the Pacific Region by 
providing hands-on training in library preparation and metabolite analysis, hosting an international summer 
school on fundamental microbiome research methods, and facilitating outreach efforts to characterize 
Hawai'i's microbiome. 
 !

## Key facts

- **NIH application ID:** 10488601
- **Project number:** 5P20GM125508-05
- **Recipient organization:** UNIVERSITY OF HAWAII AT MANOA
- **Principal Investigator:** JOANNE Y YEW
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $140,773
- **Award type:** 5
- **Project period:** 2018-08-15 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10488601

## Citation

> US National Institutes of Health, RePORTER application 10488601, Microbial Genomics and Analytical Laboratory (M-GAL) (5P20GM125508-05). Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/grant/nih/10488601. Licensed CC0.

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