# Gynecologic Biospecimen Pathology Core

> **NIH NIH P20** · NORTHWESTERN UNIVERSITY · 2022 · $167,238

## Abstract

ABSTRACT
The Robert H. Lurie Comprehensive Cancer Center (LCC) of Northwestern University has strongly endorsed
and agreed to share its Pathology Core Facility (LCC PCF) with NU-CHERS investigators through the
establishment of the NU-CHERS Gynecologic Biospecimen Pathology Shared Resource Core (GBPC) in
furtherance of the overarching goal of the NU-CHERS P20 application to support innovative translational
research to elucidate and eliminate a broad spectrum of gynecologic cancer disparities. The GBPC will maintain
the NU-CHERS Community Gynecologic Biobanking Collection (CGBC), enhancing the LCC PCF biospecimen
collection by procuring a robust and diverse collection of gynecologic cancer specimens from Chicago’s largest
public hospital, the John H. Stroger Jr, Hospital of Cook County (SHCC). The Director of the LCC-PCF, Jian-
Jun Wei, MD is Co-Director of the NU-CHERS GBPC, underscoring the commitment of the LCC PCF to the
infrastructure development and translational research proposed in the NU-CHERS application to reduce
gynecologic cancer disparities. Working in tandem with Dr. Wei is GBPC Co-Director, Thomas Lad, MD who is
Principal Investigator of the SHCC’s Minority Underserved NCI Community Oncology Research Program. The
GBPC has the following Specific Aims. Aim 1: Engage NU-CHERS affiliated site John H. Stroger Jr, Hospital of
Cook County in developing the Community Gynecologic Biobanking Collection (CGBC) a comprehensive
biorepository of well-defined gynecologic tumor types, paired with clinical and pathologic data, from racial/ethnic
minority and reference populations. Aim 2: Provide research histology and pathology services to NU-CHERS
investigations of molecular-based gynecologic cancer disparities in minority populations. Aim 3: Support clinical
trials led by NU-CHERS investigators and aimed at minimizing molecular-based gynecologic cancer disparities
in minority populations that require the analysis of correlative components. Aim 4: Expand community-engaged
research capacity among NU-CHERS research project and DRP investigators through community-tailored,
reciprocal education and training in the procurement of racial/ethnic minority biospecimen. Aim 5: Participate in
ongoing evaluation and transition planning to develop GBPC into a full P50 SPORE shared resource core.

## Key facts

- **NIH application ID:** 10488644
- **Project number:** 5P20CA233304-03
- **Recipient organization:** NORTHWESTERN UNIVERSITY
- **Principal Investigator:** Jian-Jun Wei
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $167,238
- **Award type:** 5
- **Project period:** 2020-09-17 → 2025-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10488644

## Citation

> US National Institutes of Health, RePORTER application 10488644, Gynecologic Biospecimen Pathology Core (5P20CA233304-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10488644. Licensed CC0.

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