# Pilot Research Project Core E

> **NIH NIH P30** · CASE WESTERN RESERVE UNIVERSITY · 2022 · $320,120

## Abstract

Project Summary - Pilot Research Project Core E
The CWRU Center for Excellence on the Impact of Substance Use on HIV Pilot Research
Project Core stimulates innovative investigator-initiated Substance use-related clinical,
translational, and basic science research activities. The Pilot Research Project Core will be the
focus for all of the mentoring and training activities of the Center for Excellence. The key program
funded by the Core is the award of three annual pilot grants of $65,000 to early-career and Under-
Represented in Medicine (URiM) investigators or more senior investigators who will be
encouraged to pursue research in Substance Use. These pilot awards will be linked to one-on-
one mentoring programs designed to enhance our junior and URiM faculty’s competitiveness for
federal grants. Case Western Reserve University and the Program Director of this Center have
significant experience in supporting junior and URiM investigators in advancing their careers.
Since 2008, the CWRU School of Medicine, with support from the NIH, has invested $1,183,068
in its Mentored Scientist Pilot Grants. These awardees have received $19,423,434 in research
funding as a result of their awards or a 16.4-fold return on investment. The CWRU Center for
Excellence Pilot Project Core will strive to match and exceed this record and develop new
investigators in the field of Substance Use research. Both applicants and awardees of these Pilot
Project Awards and URiM investigators will be asked to participate in a one-on-one mentoring
program, organized by the Core. Our institution, through the Strategic Investment Fund, will also
provide support for this CWRU Center for Excellence by providing matching $65,000 seed funding
for a fourth annual Pilot Award in which junior and URiM faculty take a leading role and invest
$35,000 to promote Center growth and Core utilization and provide travel and other support for
junior and underrepresented investigators. While the pilot awards expend NIH funds to support
single investigator projects by new investigators, our Strategic Investment Fund, which exclusively
uses institutional resources, supports teams that include outstanding young and URiM
investigators in a leading role and also include established investigators. A total commitment from
the Strategic Investment Fund for $500,000 has been made to this program. The specific aims of
the Core are as follows:
• Conduct responsive Pilot Research Grant programs that accelerate junior and URiM
 faculty development and encourage established investigators to expand into Substance
 use research.
• Identify, mentor, and support the next generation of Substance Use investigators.
• Train and provide support to Substance Use researchers in the planning and conduct of
 ethically sound, rigorous, and responsibly conducted research.

## Key facts

- **NIH application ID:** 10489358
- **Project number:** 5P30DA054557-02
- **Recipient organization:** CASE WESTERN RESERVE UNIVERSITY
- **Principal Investigator:** Alan David Levine
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $320,120
- **Award type:** 5
- **Project period:** 2021-09-15 → 2026-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10489358

## Citation

> US National Institutes of Health, RePORTER application 10489358, Pilot Research Project Core E (5P30DA054557-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10489358. Licensed CC0.

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