# Dissemination of libRoadRunner and CompuCell3D

> **NIH NIH U24** · UNIVERSITY OF WASHINGTON · 2022 · $301,945

## Abstract

Project Summary/Abstract
This proposal will make Virtual Tissue modeling, which spans scales from subcellular biological
networks through cells to tissues and whole organisms and populations, more accessible and
useful to biomedical researchers by improving and integrating two open-source computational
modeling environments, subcellular Tellurium, and multicellular CompuCell3D (CC3D). Both
tools aim to simplify model design by separating biologically-motivated model specification from
the computer code which runs the simulation. Impediments to adoption of Virtual Tissue
modeling include: 1) lack of familiarity, 2) substantial effort required to learn to design, build,
execute and apply models and 3) concern over sustainability if software tools disappear or if
users need to migrate between platforms. To address these concerns, we will: 1) Apply a design
architecture based on documented and tested reusable software components to harden and
integrate Tellurium and CompuCell3D, improving long term sustainability by simplifying open-
source development. 2) Streamline the learning process for model specification, execution, and
analysis to reduce barriers to adoption; 3) Simplify and harmonize installation and use across
desktop, HPC and web (cloud/cluster) installations, and 4) Disseminate upgraded tools and
expand the user and developer base via workshops, support infrastructure and online tutorials.

## Key facts

- **NIH application ID:** 10489824
- **Project number:** 5U24EB028887-04
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** James Alexander Glazier
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $301,945
- **Award type:** 5
- **Project period:** 2019-09-30 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10489824

## Citation

> US National Institutes of Health, RePORTER application 10489824, Dissemination of libRoadRunner and CompuCell3D (5U24EB028887-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10489824. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*