SUMMARY - CORE 3: Administrative Core (ADM) The Administrative Core (ADM) of the Program Project in Structural Cell Biology of DNA Repair Machines (SBDR) will coordinate all administrative aspects of the Program and facilitate interaction among the Investigators. Our goal is to maintain the SBDR program coherence, focus, and progress to ensure the successful conduct of the proposed research. Specifically, the ADM Core will provide administrative infrastructure, ensure milestones are met, and promote interaction and efficient communication among SBDR Projects and Cores and with the wider DNA repair and cancer research communities. The infrastructure for the ADM Core is already in place and operating efficiently, having been established during the 19-year history of SBDR. The ADM Core goals will be accomplished through three Specific Aims: Aim 1: Provide fiscal management support to the Program. Aim 2: Ensure effective communication among SBDR Program members. Aim 3: Monitor SBDR progress and Core Usage. Management of the SBDR Program will be provided by an administrative structure that formally consists of Drs. Susan Tsutakawa and John Tainer as ADM co-Directors, together with the Program Administrator and an Executive Committee comprised of the Project Leaders and selected additional senior co-Investigators. An External Advisory Board comprised of leading investigators in DNA repair, structural biology, and cancer biology will annually review the progress of the Program and make recommendations to SBDR PI John Tainer. The successful operation of the SBDR Program for 18 investigators at 15 institutions depends heavily on excellent communications and program management capabilities. The ADM Core serves to provide a central point of contact for all operational matters with in SBDR. This includes providing budget management, coordinating preparation of annual progress reports, monitoring progress toward overall SBDR goals, maintaining effective and equitable access to the shared resource Cores, and organizing regular webinars, and annual workshops for all investigators and SBDR fellows.