# Data Core – Improving Provider Announcement Communication Training (IMPACT)

> **NIH NIH P01** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2022 · $217,358

## Abstract

ABSTRACT – Data Core
The Data Core will centralize data-related services across research projects for the P01 Program Project, 
“Improving Provider Announcement Communication Training (IMPACT),” at the University of North Carolina. 
The IMPACT Program Project will make a significant contribution to cancer prevention by developing new 
evidence on effective strategies to improve provider communication and human papillomavirus (HPV) vaccine 
uptake. Drs. Justin Trogdon and Nisha Gottfredson will be the co-leads of the Data Core. The Data Core’s 
functions include managing a national primary care team survey, cleaning and standardizing effectiveness data 
across research projects and providing statistical support for randomization and analysis. The three Specific 
Aims of the Data Core are as follows. Aim 1 is to develop, oversee, and manage the national primary care 
team survey. The Data Core will survey 2,500 primary care team members: 1,500 HPV vaccine providers 
(physicians, physician assistants, and nurse practitioners) and 1,000 registered nurses and medical assistants 
involved in adolescent vaccination. The Data Core will be responsible for coordinating and integrating survey 
measures for use across projects, collaborating with the survey subcontractor to oversee survey 
implementation, and managing and preparing data for use by the research projects. Aim 2 is to facilitate 
access to, and standardize the structure of, large vaccination datasets generated by research project 
randomized clinical trials. The Data Core will be a central hub for managing, harmonizing, storing, and 
distributing randomized clinical trial vaccine outcomes data that will be used to evaluate intervention impact 
across Projects 1 through 3. The Core will also provide the resulting data to Project 4 to support budget impact 
and cost-effectiveness modelling. Aim 3 is to provide statistical and methodological support to research 
projects. The Data Core team will connect project investigators with appropriate statistical and study design 
expertise to design and consult on analyses as needed by the research projects. The Data Core activities will 
result in a national primary care team survey, high-quality, standardized data and appropriate and rigorous 
statistical analysis in an efficient manner that will increase the collective scientific impact of the P01 Program 
Project. The Data Core addresses the IMPACT Program Project theme by helping the research projects to 
build capacity for HPV vaccine communication interventions among primary care teams in healthcare systems.

## Key facts

- **NIH application ID:** 10493214
- **Project number:** 5P01CA250989-02
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** Tara L Queen
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $217,358
- **Award type:** 5
- **Project period:** 2021-09-23 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10493214

## Citation

> US National Institutes of Health, RePORTER application 10493214, Data Core – Improving Provider Announcement Communication Training (IMPACT) (5P01CA250989-02). Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/grant/nih/10493214. Licensed CC0.

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