# Clemson University Genomics and Bioinformatics Facility (CUGBF)

> **NIH NIH P20** · CLEMSON UNIVERSITY · 2022 · $467,179

## Abstract

Project Summary/Abstract
Genomics and bioinformatics are the currency in today’s Life Science research. A major obstacle
for junior faculty from IDeA states is the lack of state-of-the-art facilities and training opportunities
commonly found in states with substantial NIH funding. This often hinders the generation of
preliminary data necessary to be competitive for NIH R01 funding. The implementation of
advanced tools to measure and interpret gene dynamics and genomic architecture is vital to the
study of eukaryotic pathogens for the development of therapeutic intervention. Genomic level
analyses and bioinformatics are a developing field, with rapidly emerging new standards and
technologies that provide insight into the fundamentals of eukaryotic biology. Most life science
researchers are not experienced in the use of bioinformatics and genomics. Therefore, we
propose the continuation of the bioinformatics specialists hired under COBRE Phase I, hire an
additional wet lab technician to handle our rapidly increasing load and then bolster the genomics,
computational and bioinformatic infrastructure and educational outreach via the Clemson
University Genomics and Bioinformatics Facility (CUGBF) throughout Phase II. The enhanced
CUGBF is structured into three complementary parts: 1) a molecular laboratory with genomics
and next-generation sequencing (NGS) resources, 2) a bioinformatics laboratory with high
performance computing resources, & 3) the personnel and equipment at the Clemson University
Center for Human Genetics- Genomics Sciences laboratory (CUCHG-GSL which is supported by
a COBRE in Human Genetics). Having all three allows the enhanced CUGBF to offer a
comprehensive service package from extraction and next-generation sequencing of nucleic acid
to the complex data analysis and interpretation. Through this model, CUGBF has designed,
executed, and educated EPIC TIs and CU faculty to enable the integration of genomics and
bioinformatics into their research programs. The Primary goal of this COBRE Phase II core
enhancement proposal is to continue to enhance the current physical and human capital for
genomics and computational infrastructure of the CUGBF and integrate genomic data and
computational resources into the TI’s and CU faculty research programs.

## Key facts

- **NIH application ID:** 10494464
- **Project number:** 1P20GM146584-01
- **Recipient organization:** CLEMSON UNIVERSITY
- **Principal Investigator:** CHRISTOPHER L PARKINSON
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $467,179
- **Award type:** 1
- **Project period:** 2022-07-15 → 2027-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10494464

## Citation

> US National Institutes of Health, RePORTER application 10494464, Clemson University Genomics and Bioinformatics Facility (CUGBF) (1P20GM146584-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10494464. Licensed CC0.

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