# Core 2: Biostatistics and BioInformatics Core

> **NIH NIH P50** · UNIVERSITY OF WISCONSIN-MADISON · 2022 · $291,332

## Abstract

PROJECT SUMMARY
The objective of the Biostatistics and Bioinformatics Core (Biostats Core) of the Wisconsin Head and Neck
Cancer (HNC) SPORE is to promote excellence in HNC translational research by providing dedicated and
outstanding biostatistical and bioinformatic consultation and collaborative support to the HN SPORE projects,
Pathology Core, Administrative Core, and other investigators whose projects are supported under the
Developmental Research and Career Enhancement Programs. This support and collaboration will include
laboratory, translational, and clinical-based research, focusing on translation from laboratory studies to clinical
studies. The Biostats Core will achieve its objective by supporting investigators and providing statistical,
informatic, and data management expertise, thus enhancing the quality and ensuring the validity of the research
undertaken in the HN SPORE. The Biostats Core will provide expertise in all stages of the research: from
formulation of research questions through study experimental design, data collection and management, to data
analysis, interpretation and dissemination of results through publications.
The Specific Aims of the Core are:
 Aim 1. To maintain devoted collaboration with the HN SPORE investigators in the design of research studies,
 in analysis and interpretation of data, and in writing of scientific manuscripts disseminating the HN SPORE
 results to the scientific community.
 Aim 2. To upgrade the current HN SPORE data architecture to a single and unified environment that
 enhances the current database management activities to ensure the transparency and validity of statistical
 and bioinformatic analysis via centralized data management and standardization, confidential and secure
 data archiving and sharing, and data validation and consistency check.
 Aim 3. To conduct, when necessary, methodology research to develop new statistical and bioinformatic
 methods and software relevant to the HN SPORE projects.

## Key facts

- **NIH application ID:** 10495297
- **Project number:** 2P50CA278595-06A1
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **Principal Investigator:** Menggang Yu
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $291,332
- **Award type:** 2
- **Project period:** 2016-08-02 → 2027-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10495297

## Citation

> US National Institutes of Health, RePORTER application 10495297, Core 2: Biostatistics and BioInformatics Core (2P50CA278595-06A1). Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/grant/nih/10495297. Licensed CC0.

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