PROJECT SUMMARY/ABSTRACT The purpose of the Administrative Core is to support the translational research objectives of our SPORE in Prostate Cancer by serving as the organizational hub, optimizing collaboration among SPORE investigators. The specific aims of the Administrative Core are (1) provide coordination for all scientific and educational activities of the SPORE, and (2) provide centralized administrative support of day-to-day activities to all the components of the SPORE: research projects, cores, and developmental research and career enhancement programs. The services centralized in the Administrative Core provide the following administrative and communications infrastructure that serve all components of the SPORE. * Financial Management: serving as the centralized SPORE budgetary coordinator and financial manager * Grants Administration: serving as administrative liaison to the National Cancer Institute, ensuring the timely submission of all required reports and compliance with institutional and federal regulations, as well as the annual solicitation of new pilot and career projects * Patient Advocacy: developing initiatives to enhance patient and community engagement and increase clinical trial enrollment, particularly among patients from minority and underserved populations * Meetings Coordination: organize the scientific review of ongoing SPORE research projects, cores, and pilot and career projects * Communication: foster communication and collaborative research within our SPORE as well as with other prostate SPOREs, the Prostate Cancer Clinical Trials Consortium, and the wider scientific community * Editorial Services: providing editorial services for manuscript publication and ensuring compliance with public access requirements for SPORE-funded science * Data Management: supporting the maintenance and enhancement of data management systems for multiple types of research data and ensuring deposition of relevant genomic data in appropriate repositories The Administration Core is led by Howard I. Scher, MD, and Yu Chen, MD, PhD, who oversee all SPORE activities along with SPORE Executive Committee members Charles L. Sawyers, MD, and Michael J. Morris, MD. Patient advocacy efforts will be led by Susan F. Slovin, MD, PhD. The Administrative Core also includes personnel trained in financial management, grants administration, medical editing, data management, and clerical support.